MICB 产品
(MHC Class I Polypeptide-Related Sequence B (MICB))
Categories
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules\; however, it does not associate with beta-2-microglobulin or bind peptides. [provided by RefSeq, Jul 2008].
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Featured MICB Categories
MICB 抗体
High quality antibodies with extensive validation data.
MICB ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MICB 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MICB 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IP
Validations
- (1)
Cat. No.
ABIN517933
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1327622
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (1)
Cat. No.
ABIN7092967
Quantity
100 μg
Datasheet
Datasheet
Recommended MICB ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975551
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1672867
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6719775
Quantity
1 kit
Datasheet
Datasheet
Recommended MICB 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN6964108
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275257
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275258
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MICB Products
: "Combination treatment with decitabine and ionizing radiation enhances tumor cells susceptibility of T cells." in: Scientific reports, Vol. 6, pp. 32470, (2016) (PubMed).: "NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity." in: The Journal of investigative dermatology, Vol. 135, Issue 5, pp. 1311-9, (2015) (PubMed).
: "Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids." in: BMC cancer, Vol. 15, pp. 351, (2015) (PubMed).
: "Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 2, pp. 736-48, (2015) (PubMed).
: "Altered microRNA expression after infection with human cytomegalovirus leads to TIMP3 downregulation and increased shedding of metalloprotease substrates, including MICA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 3, pp. 1344-52, (2014) (PubMed).
: "Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor." in: Cancer cell international, Vol. 14, Issue 1, pp. 100, (2014) (PubMed).
: "MicroRNA editing facilitates immune elimination of HCMV infected cells." in: PLoS pathogens, Vol. 10, Issue 2, pp. e1003963, (2014) (PubMed).
: "Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation." in: PLoS pathogens, Vol. 10, Issue 5, pp. e1004058, (2014) (PubMed).
: "Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXR? activation." in: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2675-92, (2013) (PubMed).
: "Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44." in: Journal of virology, Vol. 86, Issue 16, pp. 8693-704, (2012) (PubMed).
Synonyms and alternative names related to MICB
MHC class I polypeptide-related sequence B (MICB), MHC class I-related protein-like (LOC512825), PERB11.2Protein level used designations for MICB
- MHC class I chain-related protein B
- MHC class I mic-B antigen
- MHC class I-like molecule PERB11.2-IMX
- MIC-B
- stress inducible class I homolog
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