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MFN2 产品

(Mitofusin 2 (MFN2))
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

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Featured MFN2 Categories

MFN2 抗体

High quality antibodies with extensive validation data.

MFN2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MFN2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MFN2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (8)
  • (7)
Cat. No. ABIN564263
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (5)
Cat. No. ABIN682528
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN6143800
Quantity 100 μL
Datasheet Datasheet

Recommended MFN2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6968636
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957855
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN435454
Quantity 96 tests
Datasheet Datasheet

Recommended MFN2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310805
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2726078
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505289
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MFN2 Products

Mandik, Kanana, Rody, Misera, Wilken, Laabs von Holt, Klein, Vos: "A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities." in: Frontiers in cell and developmental biology, Vol. 10, pp. 1000553, (2022) (PubMed).

Aydogan Mathyk, Temel Yuksel, Tayyar, Aslan Cetin, Tayyar, Koroglu: "Maternal serum mitofusin-2 levels in patients with preeclampsia: the possible role of mitochondrial dysfunction in preeclampsia." in: The journal of maternal-fetal & neonatal medicine, pp. 1-6, (2019) (PubMed).

Meng, Liu, Liu, Song, Liu, Xie, Han, Ji: "Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner." in: British journal of pharmacology, Vol. 175, Issue 8, pp. 1126-1145, (2018) (PubMed).

Zhou, Zhang, He, Zhuang, Han, Jiang, Yao, Huang, Ling, Lin, Lin: "Downregulation of mitochondrial cyclooxygenase-2 inhibits the stemness of nasopharyngeal carcinoma by decreasing the activity of dynamin-related protein 1." in: Theranostics, Vol. 7, Issue 5, pp. 1389-1406, (2018) (PubMed).

Li, Chen, Sun, Pang: "Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8510805, (2018) (PubMed).

Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

Yamauchi, Yamamura, Katase, Itadani, Okada, Kobiki, Nakamura, Yamaguchi, Kuribayashi: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." in: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).

Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).

Siu, Zhou, Yu, Zhang, Wang, Liang, Chen, Chan, Yu: "Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation." in: Scientific reports, Vol. 6, pp. 23464, (2016) (PubMed).

Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).

Synonyms and alternative names related to MFN2

mitofusin 2 (MFN2), Mitochondrial assembly regulatory factor (Marf), mitofusin 2 (mfn2), mitofusin-2 (LOC100186475), mitofusin 2 (Mfn2), mitofusin 2 L homeolog (mfn2.L), anon-WO0125274.3, CG3869, cmt2a, CMT2A, cmt2a2, CMT2A2, cprp1, CPRP1, D630023P19Rik, Dmel\\CG3869, dMFN, dMfn, dmfn, Fzo, hsg, HSG, MARF, marf, Marf-1, Mfn, mfn, mfn2, MFN2, mg:cb01g09, si:dkeyp-104h9.2, wu:fb79a11

Protein level used designations for MFN2

  • CG3869-PA
  • CG3869-PB
  • CG3869-PC
  • Marf-PA
  • Marf-PB
  • Marf-PC
  • drosophila mitofusin
  • mitochondrial assembly regulatory factor
  • mitofusin
  • mitofusin 2
  • mitofusin-2
  • mitofusin-2-like
  • hyperplasia suppressor
  • transmembrane GTPase MFN2
  • HSG protein
  • hypertension related protein 1
  • hypertension-related protein 1
  • hypertension-related protein
  • mitochondrial transmembrane GTPase FZO1A
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