METAP2 产品
(Methionyl Aminopeptidase 2 (METAP2))
Categories
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Jul 2008].
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Featured METAP2 Categories
METAP2 抗体
High quality antibodies with extensive validation data.
METAP2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
METAP2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended METAP2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), IF, FACS
Validations
- (11)
Cat. No.
ABIN1491153
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7159581
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN524383
Quantity
50 μg
Datasheet
Datasheet
Recommended METAP2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6968594
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957795
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957796
Quantity
96 tests
Datasheet
Datasheet
Recommended METAP2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7320247
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415242
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399430
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our METAP2 Products
: "Negative regulation of the protection of eIF2alpha phosphorylation activity by a unique acidic domain present at the N-terminus of p67." in: Experimental cell research, Vol. 283, Issue 2, pp. 237-46, (2003) (PubMed).: "Physiologically relevant metal cofactor for methionine aminopeptidase-2 is manganese." in: Biochemistry, Vol. 42, Issue 17, pp. 5035-42, (2003) (PubMed).
: "Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4." in: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26396-402, (2002) (PubMed).
Synonyms and alternative names related to METAP2
methionyl aminopeptidase 2 L homeolog (metap2.L), methionyl aminopeptidase 2 (METAP2), methionyl aminopeptidase 2 (metap2), methionine aminopeptidase 2 (LOC551771), methionine aminopeptidase 2 (metap2), methionine aminopeptidase (CAALFM_C604080WA), methionine aminopeptidase 2 (Metap2), methionyl aminopeptidase 2 S homeolog (metap2.S), methionyl aminopeptidase 2 (Metap2), methionyl aminopeptidase 2b (metap2b), 4930584B20Rik, A930035J23Rik, AI047573, AL024412, Amp2, AU014659, DDBDRAFT_0190923, DDBDRAFT_0304991, DDB_0190923, DDB_0304991, GB13458, MAP2, metap2, METAP2, MGC53792, Mnpep, MNPEP, p67, p67eIF2, wu:fb98h06, zgc:66250Protein level used designations for METAP2
- methionine aminopeptidase 2
- methionyl aminopeptidase 2
- methionine aminopeptidase 2-like
- hypothetical protein
- MAP 2
- eIF-2-associated p67
- initiation factor 2-associated 67 kDa glycoprotein
- initiation factor 2-associated protein (p67)
- metAP 2
- peptidase M 2
- eIF-2-associated p67 homolog
- initiation factor 2 associated 67 kDa protein
- p67eIF2
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