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Metabotropic Glutamate Receptor 4 蛋白

(Glutamate Receptor, Metabotropic 4 (GRM4))

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Metabotropic Glutamate Receptor 4 蛋白 (ABIN1330187)

GRM4 宿主: 人宿主: 小麦胚 Recombinant AP

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Metabotropic Glutamate Receptor 4 蛋白 (ABIN7538303)

GRM4 宿主: 人宿主: Mammalian Cells Synthetic Nanodisc

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Find Metabotropic Glutamate Receptor 4 蛋白 for a variety of species such as anti-Human Metabotropic Glutamate Receptor 4. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular Metabotropic Glutamate Receptor 4 蛋白

Product

Reactivity

Source

Validations

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Quantity

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Metabotropic Glutamate Receptor 4 蛋白

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1330187

Quantity 10 μg

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Metabotropic Glutamate Receptor 4 蛋白

Reactivity Human

Source Mammalian Cells

Validations

Cat. No. ABIN7538303

Quantity 50 μg

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Aliases for Metabotropic Glutamate Receptor 4 蛋白

glutamate metabotropic receptor 4 (GRM4) 蛋白
glutamate receptor, metabotropic 4 (Grm4) 蛋白
glutamate metabotropic receptor 4 (Grm4) 蛋白
glutamate receptor, metabotropic 4 (GRM4) 蛋白
GPRC1D 蛋白
Gprc1d 蛋白
mGlu4 蛋白
MGLUR4 蛋白
mGluR4 蛋白

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