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Metabotropic Glutamate Receptor 1 蛋白

(Glutamate Receptor, Metabotropic 1 (GRM1))

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms\; some of which may have distinct functions. [provided by RefSeq, Jul 2008].

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Metabotropic Glutamate Receptor 1 Protein (AA 387-486) (GST tag) (ABIN1355775)

GRM1 宿主: 人宿主: 小麦胚 Recombinant WB, AA, AP, ELISA

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GRM1 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, Imm, PC, SDS

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Metabotropic Glutamate Receptor 1 蛋白 (ABIN7538301)

GRM1 宿主: 人宿主: Mammalian Cells Synthetic Nanodisc

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Popular Metabotropic Glutamate Receptor 1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Metabotropic Glutamate Receptor 1 Protein (AA 387-486) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1355775

Quantity 10 μg

Datasheet Datasheet

Metabotropic Glutamate Receptor 1 Protein (AA 165-592) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7407208

Quantity 100 μg

Datasheet Datasheet

Metabotropic Glutamate Receptor 1 蛋白

Reactivity Human

Source Mammalian Cells

Validations

Cat. No. ABIN7538301

Quantity 50 μg

Datasheet Datasheet

Aliases for Metabotropic Glutamate Receptor 1 蛋白

glutamate metabotropic receptor 1 (GRM1) 蛋白
glutamate receptor, metabotropic 1a (grm1a) 蛋白
metabotropic glutamate receptor 1 (mGlutR1) 蛋白
glutamate receptor, metabotropic 1 (Grm1) 蛋白
glutamate receptor, metabotropic 1 (GRM1) 蛋白
4930455H15Rik 蛋白
ENSMUSG00000075319 蛋白
fj39d05 蛋白
GB18621 蛋白
Glura 蛋白
Gm10828 蛋白
GPRC1A 蛋白
Gprc1a 蛋白
MGLU1 蛋白
MGLUR1 蛋白
mGluR1 蛋白
mGlutR 蛋白
nmf373 蛋白
rcw 蛋白
SCAR13 蛋白
si:ch211-51a19.1 蛋白
wobl 蛋白
wu:fj39d05 蛋白

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Aliases for Metabotropic Glutamate Receptor 1 蛋白

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