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Mesp2 产品

(Mesoderm Posterior 2 Homolog (Mesp2))

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This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). [provided by RefSeq, Oct 2008].

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Featured Mesp2 Categories

Mesp2 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our Mesp2 Products

Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: "Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis." in: Studies in health technology and informatics, Vol. 176, pp. 52-5, (2012) (PubMed).

Cornier, Staehling-Hampton, Delventhal, Saga, Caubet, Sasaki, Ellard, Young, Ramirez, Carlo, Torres, Emans, Turnpenny, Pourquié: "Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1334-41, (2008) (PubMed).

Leschik, Stefanovic, Brinon, Pucéat: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).

Synonyms and alternative names related to Mesp2

mesoderm posterior 2 (Mesp2), mesoderm posterior bHLH transcription factor 2 (Mesp2), mesoderm posterior bHLH transcription factor 2 (MESP2), bHLHc6, SCDO2

Protein level used designations for Mesp2

  • mesoderm posterior protein 2
  • mesoderm posterior 2
  • class C basic helix-loop-helix protein 6
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