Mesothelin 产品
(Mesothelin (MSLN))
Categories
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
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Featured Mesothelin Categories
Mesothelin 抗体
High quality antibodies with extensive validation data.
Mesothelin ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Mesothelin 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Mesothelin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC (f)
Validations
- (7)
Cat. No.
ABIN6939032
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, FACS, IHC (p)
Validations
- (5)
Cat. No.
ABIN727608
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (f)
Validations
- (5)
Cat. No.
ABIN7504135
Quantity
100 μg
Datasheet
Datasheet
Recommended Mesothelin ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957762
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957761
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6976025
Quantity
96 tests
Datasheet
Datasheet
Recommended Mesothelin 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275282
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275288
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275283
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Mesothelin Products
: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." in: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).: "A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma." in: EBioMedicine, Vol. 61, pp. 103031, (2021) (PubMed).
: "Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer." in: BMC cancer, Vol. 18, Issue 1, pp. 1254, (2019) (PubMed).
: "Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy." in: Human gene therapy, Vol. 29, Issue 5, pp. 614-625, (2019) (PubMed).
: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." in: Biotechnology and bioengineering, (2019) (PubMed).
: "Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 102, (2018) (PubMed).
: "Efficacy of Anti-mesothelin Immunotoxin RG7787 plus Nab-Paclitaxel against Mesothelioma Patient-Derived Xenografts and Mesothelin as a Biomarker of Tumor Response." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 6, pp. 1564-1574, (2018) (PubMed).
: "Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression." in: Frontiers in oncology, Vol. 8, pp. 40, (2018) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." in: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy." in: Oncotarget, Vol. 9, Issue 3, pp. 3895-3907, (2018) (PubMed).
Synonyms and alternative names related to Mesothelin
mesothelin (MSLN), mesothelin (Msln), mesothelin (LOC611363), mesothelin (LOC100524016), MPF, MSLN, SMRPProtein level used designations for Mesothelin
- CAK1 antigen
- megakaryocyte potentiating factor
- pre-pro-megakaryocyte-potentiating factor
- soluble MPF mesothelin related protein
- ERC/mesothelin
- protein expressed in renal carcinoma
- mesothelin
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