Merlin 抗体
(Neurofibromin 2 (NF2))
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development\; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008].
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Popular Merlin 抗体
Product
Reactivity
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (6)
Cat. No.
ABIN6144548
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7434395
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7441928
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7159413
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7138643
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN1327740
Quantity
50 μL
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256364
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP
Validations
- (4)
- (2)
Cat. No.
ABIN104130
Quantity
100 μg
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6263224
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN6144550
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN390756
Quantity
400 μL
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Datasheet
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Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN2789402
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN1532019
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN685522
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN744128
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Merlin 抗体
: "An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice." in: Cell stem cell, Vol. 21, Issue 1, pp. 91-106.e6, (2018) (PubMed).: "Influence of Membrane Receptor Lateral Diffusion on the Short-Term Depression of Acetylcholine-Induced Current in Helix Neurons." in: Cellular and molecular neurobiology, (2017) (PubMed).
: "Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP." in: Genes & development, Vol. 29, Issue 12, pp. 1285-97, (2015) (PubMed).
: "Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators." in: Development (Cambridge, England), Vol. 140, Issue 16, pp. 3323-34, (2013) (PubMed).
: "Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast." in: PLoS ONE, Vol. 7, Issue 11, pp. e48897, (2012) (PubMed).
: "Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways." in: Molecular cancer therapeutics, (2011) (PubMed).
: "The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals." in: Developmental cell, Vol. 19, Issue 1, pp. 27-38, (2010) (PubMed).
: "Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells." in: Journal of cell science, Vol. 122, Issue Pt 22, pp. 4141-9, (2010) (PubMed).
: "The phosphorylation status of merlin in sporadic vestibular Schwannomas." in: Molecular and cellular biochemistry, Vol. 324, Issue 1-2, pp. 201-6, (2009) (PubMed).
: "Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells." in: Cancer research, Vol. 66, Issue 5, pp. 2708-15, (2006) (PubMed).
Aliases for Merlin 抗体
neurofibromin 2 (NF2) 抗体neurofibromin 2 (Nf2) 抗体
neurofibromin 2a (merlin) (nf2a) 抗体
neurofibromin 2b (merlin) (nf2b) 抗体
neurofibromin 2 (merlin) S homeolog (nf2.S) 抗体
ACN 抗体
BANF 抗体
merlin 抗体
NF2 抗体
nf2 抗体
NF2a 抗体
SCH 抗体
zgc:194620 抗体
zgc:194631 抗体
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