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Melanophilin 抗体

(Melanophilin (MLPH))
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
Melanophilin 抗体  (AA 310-539) Melanophilin 抗体  (AA 310-539) Melanophilin 抗体 (AA 310-539) (ABIN7159304)

MLPH 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

Melanophilin 抗体 Melanophilin 抗体 Melanophilin 抗体 (ABIN7262539)

MLPH 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

Melanophilin 抗体  (C-Term) Melanophilin 抗体  (C-Term) Melanophilin 抗体 (C-Term) (ABIN6263218)

MLPH 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

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Find Melanophilin 抗体 for a variety of species such as anti-Human Melanophilin, anti-Mouse Melanophilin, anti-Rat Melanophilin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular Melanophilin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7159304
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7262539
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6263218
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF, ICC, Pull-Down
Validations
  • (4)
  • (2)
Cat. No. ABIN184753
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN6143892
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN949629
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN6746597
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN656542
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN953384
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7159306
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7159307
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7159305
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
Cat. No. ABIN7116183
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, IP
Validations
Cat. No. ABIN7116182
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
Cat. No. ABIN7466711
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Melanophilin 抗体

Sanzà, Evans, Briggs, Cantero, Montoliu, Patel, Sviderskaya, Itzen, Figueiredo, Seabra, Hume: "Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a." in: Journal of cell science, Vol. 132, Issue 9, (2020) (PubMed).

Zhan, Yan, Wang, Sun, Wang, Lin, Zhang, Shi, Jiang, Wang: "Identification of immunohistochemical markers for distinguishing lung adenocarcinoma from squamous cell carcinoma." in: Journal of thoracic disease, Vol. 7, Issue 8, pp. 1398-405, (2015) (PubMed).

Gromov, Espinoza, Talman, Honma, Kroman, Timmermans Wielenga, Moreira, Gromova: "FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast." in: PLoS ONE, Vol. 9, Issue 11, pp. e112024, (2014) (PubMed).

Singh, Mizuno, Wasmeier, Wavre-Shapton, Recchi, Catz, Futter, Tolmachova, Hume, Seabra: "Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion." in: The FEBS journal, Vol. 280, Issue 3, pp. 892-903, (2013) (PubMed).

Figueiredo, Wasmeier, Tarafder, Ramalho, Baron, Seabra: "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23209-16, (2008) (PubMed).

Hume, Tarafder, Ramalho, Sviderskaya, Seabra: "A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes." in: Molecular biology of the cell, Vol. 17, Issue 11, pp. 4720-35, (2006) (PubMed).

Hamza, Prohaska, Gitlin: "Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 3, pp. 1215-20, (2003) (PubMed).

Matesic, Yip, Reuss, Swing, OSullivan, Fletcher, Copeland, Jenkins: "Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 18, pp. 10238-43, (2001) (PubMed).

Adler, Fuchs, Kim, Kraft, King, Pelling, Ronai: "jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 6, Issue 11, pp. 1437-46, (1996) (PubMed).

Subramaniam, Peter, Philp, Wong, Hong: "GS28, a 28-kilodalton Golgi SNARE that participates in ER-Golgi transport." in: Science (New York, N.Y.), Vol. 272, Issue 5265, pp. 1161-3, (1996) (PubMed).

Aliases for Melanophilin 抗体

melanophilin (MLPH) 抗体
melanophilin (mlph) 抗体
melanophilin (Mlph) 抗体
2210418F23Rik 抗体
5031433I09Rik 抗体
AW228792 抗体
D1Wsu84e 抗体
l(1)-3Rk 抗体
l1Rk3 抗体
ln 抗体
LOC100222096 抗体
MGC155106 抗体
Slac-2a 抗体
SLAC2-A 抗体
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