Melanophilin 产品
(Melanophilin (MLPH))
Categories
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Featured Melanophilin Categories
Melanophilin 抗体
High quality antibodies with extensive validation data.
Melanophilin ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Melanophilin 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Melanophilin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7159304
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7262539
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6263218
Quantity
100 μL
Datasheet
Datasheet
Recommended Melanophilin ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5592380
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6205901
Quantity
96 tests
Datasheet
Datasheet
Recommended Melanophilin 蛋白
Latest Publications for our Melanophilin Products
: "Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a." in: Journal of cell science, Vol. 132, Issue 9, (2020) (PubMed).: "Identification of immunohistochemical markers for distinguishing lung adenocarcinoma from squamous cell carcinoma." in: Journal of thoracic disease, Vol. 7, Issue 8, pp. 1398-405, (2015) (PubMed).
: "FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast." in: PLoS ONE, Vol. 9, Issue 11, pp. e112024, (2014) (PubMed).
: "Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion." in: The FEBS journal, Vol. 280, Issue 3, pp. 892-903, (2013) (PubMed).
: "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23209-16, (2008) (PubMed).
: "A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes." in: Molecular biology of the cell, Vol. 17, Issue 11, pp. 4720-35, (2006) (PubMed).
: "Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 3, pp. 1215-20, (2003) (PubMed).
: "Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 18, pp. 10238-43, (2001) (PubMed).
: "jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 6, Issue 11, pp. 1437-46, (1996) (PubMed).
: "GS28, a 28-kilodalton Golgi SNARE that participates in ER-Golgi transport." in: Science (New York, N.Y.), Vol. 272, Issue 5265, pp. 1161-3, (1996) (PubMed).
Synonyms and alternative names related to Melanophilin
melanophilin (MLPH), melanophilin (mlph), melanophilin (Mlph), 2210418F23Rik, 5031433I09Rik, AW228792, D1Wsu84e, l(1)-3Rk, l1Rk3, ln, LOC100222096, MGC155106, Slac-2a, SLAC2-AProtein level used designations for Melanophilin
- melanophilin
- exophilin-3
- leaden protein
- slaC2-a
- slp homolog lacking C2 domains a
- synaptotagmin-like protein 2a
您还需要查找其他产品吗？
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- Membralin
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- Membrane Protein, Palmitoylated 2 (MAGUK P55 Subfamily Member 2)
- Membrane transport protein XK
- Membrane-Spanning 4-Domains, Subfamily A, Member 8
- MEMO1
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