MED12 抗体
(Mediator Complex Subunit 12 (MED12))
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009].
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MED12 抗体 by Grade
Find MED12 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
MED12 抗体 by 适用
Find MED12 抗体 for a variety of species such as anti-Mouse MED12, anti-Human MED12, anti-Rat MED12. The species listed below are among those available. Click on a link to go to the corresponding products.
MED12 抗体 by 应用范围
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MED12 抗体 by 抗体来源
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MED12 抗体 by 抗原表位
Find MED12 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
MED12 抗体 by 克隆形成能力
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MED12 抗体 by 克隆
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Popular MED12 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN6242936
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7159104
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7243679
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
- (1)
Cat. No.
ABIN564287
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (1)
Cat. No.
ABIN5675220
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, WB, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN5675221
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6977635
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6979294
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6978496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6976774
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6980150
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6981060
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6982032
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6983572
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN6984433
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our MED12 抗体
: "H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas." in: Oncogene, Vol. 38, Issue 27, pp. 5356-5366, (2019) (PubMed).: "Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6." in: Journal of medicinal chemistry, Vol. 59, Issue 19, pp. 9124-9139, (2016) (PubMed).
: "Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 15, pp. 6679-90, (2013) (PubMed).
: "Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription." in: PLoS ONE, Vol. 8, Issue 10, pp. e78242, (2013) (PubMed).
: "Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation." in: Biochimie, Vol. 94, Issue 8, pp. 1828-32, (2012) (PubMed).
: "Control of ground-state pluripotency by allelic regulation of Nanog." in: Nature, Vol. 483, Issue 7390, pp. 470-3, (2012) (PubMed).
: "MED12 alterations in both human benign and malignant uterine soft tissue tumors." in: PLoS ONE, Vol. 7, Issue 6, pp. e40015, (2012) (PubMed).
: "Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines." in: Experimental hematology, Vol. 40, Issue 10, pp. 800-10, (2012) (PubMed).
: "A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 2, pp. 348-59, (2011) (PubMed).
: "Core promoter recognition complex changes accompany liver development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 10, pp. 3906-11, (2011) (PubMed).
Aliases for MED12 抗体
mediator complex subunit 12 (MED12) 抗体mediator complex subunit 12 (Med12) 抗体
mediator complex subunit 12 (med12) 抗体
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