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MED1 产品

(Mediator Complex Subunit 1 (MED1))
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008].

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Featured MED1 Categories

MED1 抗体

High quality antibodies with extensive validation data.

MED1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MED1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MED1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
Cat. No. ABIN6256479
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6257759
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN562335
Quantity 100 μg
Datasheet Datasheet

Recommended MED1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648137
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743266
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774171
Quantity 96 tests
Datasheet Datasheet

Recommended MED1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310628
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418785
Quantity 100 μg
Datasheet Datasheet
Reactivity Schizosaccharomyces pombe
Source Yeast
Validations
Cat. No. ABIN1617063
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MED1 Products

Brückmann, Bennedsen, Duijf, Terp, Thomassen, Larsen, Pedersen, Kruse, Alcaraz, Ditzel, Gjerstorff: "A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence." in: Cell death & disease, Vol. 10, Issue 11, pp. 841, (2019) (PubMed).

Tabata, Rodgers, Hall, Lee, Jedrychowski, Gygi, Puigserver: "Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1? and MED1 complex." in: Diabetes, Vol. 63, Issue 5, pp. 1519-32, (2014) (PubMed).

Synonyms and alternative names related to MED1

mediator complex subunit 1 (MED1), calcitonin-related polypeptide beta (CALCB), mediator complex subunit 1 (med1), Mediator complex subunit 1 (MED1), mediator complex subunit 1 (Med1), mediator of RNA polymerase II transcription subunit 1 (med1), AI480703, CG7162, CRSP-1, CRSP1, crsp1, CRSP200, crsp200, CRSP210, Dmel\\CG7162, DRIP205, drip205, DRIP230, drip230, dTRAP220, l11Jus15, MED1, Med1, Med1/SOP3/TRAP220, nbr1, PBP, pbp, PPARBP, pparbp, Pparbp, PPARGBP, ppargbp, RB18A, rb18a, RGD1559552, TRAP220, trap220, Trap220, TRIP2, trip2

Protein level used designations for MED1

  • ARC205
  • PPAR binding protein
  • PPAR-binding protein
  • PPARG binding protein
  • TR-interacting protein 2
  • TRIP-2
  • activator-recruited cofactor 205 kDa component
  • mediator of RNA polymerase II transcription subunit 1
  • p53 regulatory protein RB18A
  • peroxisome proliferator-activated receptor-binding protein
  • thyroid hormone receptor-associated protein complex 220 kDa component
  • thyroid hormone receptor-associated protein complex component TRAP220
  • thyroid receptor interacting protein 2
  • thyroid receptor-interacting protein 2
  • vitamin D receptor-interacting protein 230 kD
  • vitamin D receptor-interacting protein complex component DRIP205
  • calcitonin receptor-stimulating peptide 1
  • calcitonin receptor-stimulating peptide-1
  • calcitonin-related polypeptide, beta
  • mediator complex subunit 1
  • peroxisome proliferator-activated receptor binding protein
  • membrane component, chromosome 17, surface marker 2
  • CG7162-PA
  • CG7162-PB
  • CG7162-PC
  • MED1-PA
  • MED1-PB
  • MED1-PC
  • mediator
  • Ppar binding protein
  • peroxisome proliferator activated receptor binding protein
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