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MDM4-binding Protein ELISA试剂盒

(Mdm4-binding Protein (MDM4))

This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latter's degradation. So this protein can reverse MDM2-targeted degradation of p53, while maintaining suppression of p53 transactivation and apoptotic functions. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2011].

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MDM4-binding Protein ELISA 试剂盒 (ABIN1381305)

MDM4 适用: 人, 小鼠, 大鼠 Colorimetric Cell ELISA Cell Culture Cells

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recommended

MDM4-binding Protein ELISA 试剂盒 (ABIN6951175)

MDM4 适用: 人 Colorimetric Sandwich ELISA Cell Culture Supernatant, Cell Samples, Plasma, Serum, Tissue Lysate

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Popular MDM4-binding Protein ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

MDM4-binding Protein ELISA 试剂盒

Reactivity Human, Mouse, Rat

Analytical Method Qualitative Cell ELISA

Validations

Cat. No. ABIN1381305

Quantity 96 tests

Datasheet Datasheet

MDM4-binding Protein ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6951175

Quantity 96 tests

Datasheet Datasheet

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MDM4-binding Protein ELISA试剂盒 by 适用

MDM4-binding Protein ELISA试剂盒 by 检测方法

MDM4-binding Protein ELISA试剂盒 by Analytical Method

MDM4-binding Protein ELISA试剂盒 by 实验类型

MDM4-binding Protein ELISA试剂盒 by 样本

Popular MDM4-binding Protein ELISA试剂盒

Aliases for MDM4-binding Protein ELISA试剂盒

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