MCM7 抗体
(Minichromosome Maintenance Complex Component 7 (MCM7))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
recommended
MCM7 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 6C2 unconjugated
recommended
recommended
MCM7 抗体 by 适用
Find MCM7 抗体 for a variety of species such as anti-Human MCM7, anti-Mouse MCM7, anti-Rat MCM7. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find MCM7 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
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Popular MCM7 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human
Application
WB, IF, ELISA, IHC (p), PLA
Validations
- (4)
- (7)
Cat. No.
ABIN561764
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IF, IP
Validations
- (5)
Cat. No.
ABIN3021521
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF, IHC (p), IP, ICC, ChIP
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- (5)
Cat. No.
ABIN2856749
Quantity
100 μL
Datasheet
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Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
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- (6)
Cat. No.
ABIN3043877
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN3187879
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, StM
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Cat. No.
ABIN6940025
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6940023
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
IHC, IF, FACS, StM
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- (4)
Cat. No.
ABIN6940019
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, StM
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- (4)
Cat. No.
ABIN6940018
Quantity
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Datasheet
Datasheet
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Application
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- (3)
Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN7477515
Quantity
1 mL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF, IP
Validations
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Cat. No.
ABIN7268544
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN3044178
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our MCM7 抗体
: "JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4684-97, (2016) (PubMed).: "Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate." in: Oncotarget, Vol. 5, Issue 5, pp. 1326-37, (2014) (PubMed).
: "Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 32, pp. E3325-34, (2014) (PubMed).
: "A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication." in: Science signaling, Vol. 6, Issue 262, pp. ra10, (2013) (PubMed).
: "MCM proteins are negative regulators of hypoxia-inducible factor 1." in: Molecular cell, Vol. 42, Issue 5, pp. 700-12, (2011) (PubMed).
: "Validation of different replication markers for the detection of beta-cell proliferation in human pancreatic tissue." in: Regulatory peptides, Vol. 162, Issue 1-3, pp. 115-21, (2010) (PubMed).
: "Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion." in: Oncogene, Vol. 29, Issue 40, pp. 5475-89, (2010) (PubMed).
: "Etiological role of human papillomavirus infection for inverted papilloma of the bladder." in: Journal of medical virology, Vol. 83, Issue 2, pp. 277-85, (2010) (PubMed).
: "L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 52, pp. 22552-7, (2010) (PubMed).
: "Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins." in: Journal of virology, Vol. 82, Issue 3, pp. 1458-64, (2008) (PubMed).
Aliases for MCM7 抗体
minichromosome maintenance complex component 7 (MCM7) 抗体mini-chromosome maintenance complex protein 7 (MCM7) 抗体
mini-chromosome maintenance complex protein 7 (CDC47) 抗体
minichromosome maintenance complex component 7 (Mcm7) 抗体
minichromosome maintenance complex component 2 (MCM2) 抗体
minichromosome maintenance complex component 7 (mcm7) 抗体
minichromosome maintenance complex component 7 L homeolog (mcm7.L) 抗体
Minichromosome maintenance 7 (Mcm7) 抗体
minichromosome maintenance complex component 7 S homeolog (mcm7.S) 抗体
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