MCM10 抗体
(Minichromosome Maintenance Deficient 10 (MCM10))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
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MCM10 抗体 by 适用
Find MCM10 抗体 for a variety of species such as anti-Human MCM10, anti-Mouse MCM10, anti-Rat MCM10. The species listed below are among those available. Click on a link to go to the corresponding products.
MCM10 抗体 by 应用范围
Find MCM10 抗体 validated for a specific application such as WB, IHC, ELISA, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
MCM10 抗体 by 抗体来源
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MCM10 抗体 by 抗原表位
Find MCM10 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
MCM10 抗体 by 克隆形成能力
Find available monoclonal or polyclonal MCM10 抗体. Click on a link to go to the corresponding products.
MCM10 抗体 by 标记
Find MCM10 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Validations
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Cat. No.
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Quantity
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Quantity
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Validations
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Quantity
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Datasheet
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Latest Publications for our MCM10 抗体
: "Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140645, (2015) (PubMed).: "Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 8, pp. 842-56, (2011) (PubMed).
: "Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication." in: Molecular biology of the cell, Vol. 18, Issue 10, pp. 4085-95, (2007) (PubMed).
: "The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism." in: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30631-44, (2006) (PubMed).
Aliases for MCM10 抗体
Minichromosome maintenance 10 (Mcm10) 抗体minichromosome maintenance 10 replication initiation factor (MCM10) 抗体
minichromosome maintenance 10 replication initiation factor (Mcm10) 抗体
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