MBP 产品
(MBP)
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The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008].
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Reactivity
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Cat. No.
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Cat. No.
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Latest Publications for our MBP Products
: "Paternal bisphenol a diet changes prefrontal cortex proteome and provokes behavioral dysfunction in male offspring." in: Chemosphere, Vol. 184, pp. 720-729, (2017) (PubMed).: "MicroRNA-210 contributes to peripheral nerve regeneration through promoting the proliferation and migration of Schwann cells." in: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 2809-2816, (2017) (PubMed).
: "The proteins interacting with C-terminal of μ receptor are identified by bacterial two-hybrid system from brain cDNA library in morphine-dependent rats." in: Life sciences, Vol. 143, pp. 156-67, (2016) (PubMed).
: "Isolation of a pluripotent neural stem cell from the embryonic bovine brain." in: International journal of molecular sciences, Vol. 16, Issue 3, pp. 5990-9, (2015) (PubMed).
: "Stromal Cell-Derived Factor-1? Plays a Crucial Role Based on Neuroprotective Role in Neonatal Brain Injury in Rats." in: International journal of molecular sciences, Vol. 16, Issue 8, pp. 18018-32, (2015) (PubMed).
: "Acellular spinal cord scaffold seeded with mesenchymal stem cells promotes long-distance axon regeneration and functional recovery in spinal cord injured rats." in: Journal of the neurological sciences, Vol. 325, Issue 1-2, pp. 127-36, (2013) (PubMed).
Synonyms and alternative names related to MBP
myelin basic protein (MBP), myelin basic protein (Mbp), myelin basic protein a (mbpa), C76307, cb274, fj33b11, golli-mbp, Hmbpr, mbp, Mbps, mld, R75289, shi, wu:fj33b11, wu:fq15b02, zgc:136630Protein level used designations for MBP
- myelin A1 protein
- myelin membrane encephalitogenic protein
- myelin deficient
- shiverer
- Golli-Mbp; myelin basic protein
- Golli-Mbp; myelin basic protein; myelin basic protein S
- MBP S
- myelin basic protein Golli-mbp
- myelin basic protein S
- myelin basic protein
- 20 kDa microtubule-stabilizing protein
- microtubule-stabilizing protein
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