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MBD2 抗体

(Methyl-CpG Binding Domain Protein 2 (MBD2))
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
MBD2 抗体  (Internal Region) MBD2 抗体  (Internal Region) MBD2 抗体 (Internal Region) (ABIN334432)

Verified MBD2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

MBD2 抗体  (AA 250-279) MBD2 抗体  (AA 250-279) MBD2 抗体 (AA 250-279) (ABIN1881531)

MBD2 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41663 unconjugated

MBD2 抗体  (N-Term) MBD2 抗体  (N-Term) MBD2 抗体 (N-Term) (ABIN2779675)

MBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

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Popular MBD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (4)
Cat. No. ABIN334432
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
  • (2)
Cat. No. ABIN1881531
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (1)
  • (3)
Cat. No. ABIN2779675
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7443881
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN6242434
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1680781
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6569193
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2778640
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6742279
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN6263148
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202197
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Human, Mouse, Pig
Application WB, IHC, IP, IF, IHC (p)
Validations
  • (1)
Cat. No. ABIN2625251
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7268491
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856140
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3043613
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MBD2 抗体

Zhao, Sentürk, Song, Grummt: "lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures." in: Genes & development, Vol. 32, Issue 11-12, pp. 836-848, (2018) (PubMed).

Kim, Kwak, Weitz: "Specificity in circadian clock feedback from targeted reconstitution of the NuRD corepressor." in: Molecular cell, Vol. 56, Issue 6, pp. 738-48, (2014) (PubMed).

Bartels, Spruijt, Brinkman, Jansen, Vermeulen, Stunnenberg: "A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein." in: PLoS ONE, Vol. 6, Issue 10, pp. e25884, (2012) (PubMed).

Spruijt, Bartels, Brinkman, Tjeertes, Poser, Stunnenberg, Vermeulen: "CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex." in: Molecular bioSystems, Vol. 6, Issue 9, pp. 1700-6, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, (2010) (PubMed).

Hosgood, Menashe, He, Chanock, Lan: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).

Zhao, Wu, Bu, Lu, Liang, Cao, Tong, Lu, Wu, Guo et al.: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).

Tan, Nakielny: "Control of the DNA methylation system component MBD2 by protein arginine methylation." in: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7224-35, (2006) (PubMed).

Le Guezennec, Vermeulen, Brinkman, Hoeijmakers, Cohen, Lasonder, Stunnenberg: "MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties." in: Molecular and cellular biology, Vol. 26, Issue 3, pp. 843-51, (2006) (PubMed).

Aliases for MBD2 抗体

methyl-CpG binding domain protein 2 (MBD2) 抗体
methyl-CpG binding domain protein 2 (Mbd2) 抗体
methyl-CpG binding domain protein 2 (mbd2) 抗体
methyl-CpG binding domain protein 2 S homeolog (mbd2.S) 抗体
DMTase 抗体
MBD2 抗体
MBD2a 抗体
NY-CO-41 抗体
wu:fa97f06 抗体
zgc:111862 抗体
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