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MBD1 抗体

(Methyl-CpG Binding Domain Protein 1 (MBD1))
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011].
MBD1 抗体  (AA 415-508) MBD1 抗体  (AA 415-508) MBD1 抗体 (AA 415-508) (ABIN517760)

MBD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C7 unconjugated

MBD1 抗体  (AA 415-508) MBD1 抗体  (AA 415-508) MBD1 抗体 (AA 415-508) (ABIN517761)

MBD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F6 unconjugated

MBD1 抗体  (AA 1-605) MBD1 抗体  (AA 1-605) MBD1 抗体 (AA 1-605) (ABIN517757)

MBD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

MBD1 抗体 by 适用

Find MBD1 抗体 for a variety of species such as anti-Human MBD1, anti-Rat MBD1, anti-Dog MBD1. The species listed below are among those available. Click on a link to go to the corresponding products.

MBD1 抗体 by 应用范围

Find MBD1 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MBD1 抗体 by 抗体来源

Find MBD1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

MBD1 抗体 by 抗原表位

Find MBD1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MBD1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal MBD1 抗体. Click on a link to go to the corresponding products.

MBD1 抗体 by 克隆

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MBD1 抗体 by 标记

Find MBD1 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MBD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN517760
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN517761
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (2)
Cat. No. ABIN517757
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6263147
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7159609
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN1882100
Quantity 400 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6736735
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN2777532
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ChIP
Validations
  • (3)
Cat. No. ABIN6655183
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN517759
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (1)
Cat. No. ABIN6940006
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6972316
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN208097
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN208588
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2779420
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MBD1 抗体

Hendriks, Treffers, Verlaan-de Vries, Olsen, Vertegaal: "SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage." in: Cell reports, (2015) (PubMed).

Varshney, Vavrova-Anderson, Oler, Cowling, Cairns, White: "SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation." in: Nature communications, Vol. 6, pp. 6569, (2015) (PubMed).

Staples, Myers, Beveridge, Patil, Howard, Barone, Lee, Swanton, Howell, Maslen, Skehel, Boulton, Collis: "Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability." in: Journal of cell science, Vol. 127, Issue Pt 13, pp. 2910-9, (2014) (PubMed).

Waterfield, Khan, Cortez, Fan, Metzger, Greer, Fasano, Martinez-Llordella, Pollack, Erle, Su, Anderson: "The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance." in: Nature immunology, Vol. 15, Issue 3, pp. 258-65, (2014) (PubMed).

Staples, Myers, Beveridge, Patil, Lee, Swanton, Howell, Boulton, Collis: "The centriolar satellite protein Cep131 is important for genome stability." in: Journal of cell science, Vol. 125, Issue Pt 20, pp. 4770-9, (2012) (PubMed).

Zhao, Wu, Bu, Lu, Liang, Cao, Tong, Lu, Wu, Guo et al.: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).

Kumar, Verma: "Methods in cancer epigenetics and epidemiology." in: Methods in molecular biology (Clifton, N.J.), Vol. 471, pp. 273-88, (2008) (PubMed).

Ruddock-DCruz, Xue, Wilson, Heffernan, Prashadkumar, Cooney, Sanchez-Partida, French, Holland: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." in: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).

Villa, Pasini, Gutierrez, Morey, Occhionorelli, Viré, Nomdedeu, Jenuwein, Pelicci, Minucci, Fuks, Helin, Di Croce: "Role of the polycomb repressive complex 2 in acute promyelocytic leukemia." in: Cancer cell, Vol. 11, Issue 6, pp. 513-25, (2007) (PubMed).

Xiong, Dowdy, Eberhardt, Podratz, Jiang: "hMLH1 promoter methylation and silencing in primary endometrial cancers are associated with specific alterations in MBDs occupancy and histone modifications." in: Gynecologic oncology, Vol. 103, Issue 1, pp. 321-8, (2006) (PubMed).

Aliases for MBD1 抗体

methyl-CpG binding domain protein 1 (MBD1) 抗体
methyl-CpG binding domain protein 1 (Mbd1) 抗体
CCDC11 抗体
CXXC3 抗体
Cxxc3 抗体
PCM1 抗体
RFT 抗体
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