MARCH1 产品
(Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
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MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]\; Thibodeau et al., 2008 [PubMed 18389477]\; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010].
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Featured MARCH1 Categories
Recommended MARCH1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IF, ICC
Validations
- (2)
Cat. No.
ABIN6263124
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN7301464
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN565806
Quantity
50 μL
Datasheet
Datasheet
Recommended MARCH1 蛋白
Latest Publications for our MARCH1 Products
: "Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism." in: Frontiers in pharmacology, Vol. 12, pp. 710722, (2021) (PubMed).: "Novel regulation of MHC class II function in B cells." in: The EMBO journal, Vol. 26, Issue 3, pp. 846-54, (2007) (PubMed).
Synonyms and alternative names related to MARCH1
membrane associated ring-CH-type finger 1 (MARCH1), membrane-associated ring finger (C3HC4) 1 (March1), membrane associated ring-CH-type finger 1 (March1), 2900024D24Rik, BB085186, DKFZp459K1250, MARCH-I, MARCH1, RGD1305148, RNF171Protein level used designations for MARCH1
- E3 ubiquitin-protein ligase MARCH1
- RING finger protein 171
- membrane-associated RING finger protein 1
- membrane-associated RING-CH protein I
- MARCH-I
- membrane-associated ring finger (C3HC4) 1
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