MAPK10 抗体
(Mitogen-Activated Protein Kinase 10 (MAPK10))
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
recommended
recommended
MAPK10 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2B10H12 unconjugated
recommended
MAPK10 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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Popular MAPK10 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human
Application
WB
Validations
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Cat. No.
ABIN3022948
Quantity
100 μL
Datasheet
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Reactivity
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Application
WB, ELISA, IHC, ICC, FACS
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- (4)
Cat. No.
ABIN5542487
Quantity
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Datasheet
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Reactivity
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Application
WB, ELISA, IHC (p), ICC, IHC (fro)
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Cat. No.
ABIN7429106
Quantity
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Datasheet
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WB, ELISA, ICC
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Cat. No.
ABIN1724701
Quantity
100 μL
Datasheet
Datasheet
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Human, Mouse, Rat
Application
WB, ELISA, IHC, IF
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Cat. No.
ABIN3185272
Quantity
100 μL
Datasheet
Datasheet
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Application
WB, ELISA, IF
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- (2)
Cat. No.
ABIN562416
Quantity
100 μg
Datasheet
Datasheet
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Human, Mouse, Rat
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WB, ELISA, IF, ICC
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Cat. No.
ABIN6257975
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN207628
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Goat, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
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Cat. No.
ABIN3031827
Quantity
0.4 mL
Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
- (6)
Cat. No.
ABIN966521
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
- (6)
Cat. No.
ABIN966522
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Quantity
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Datasheet
Datasheet
Latest Publications for our MAPK10 抗体
: "EphrinB2 controls vessel pruning through STAT1-JNK3 signalling." in: Nature communications, Vol. 6, pp. 6576, (2015) (PubMed).: "Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4201-12, (2008) (PubMed).
: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).
: "Role of mitogen- and stress-activated kinases in ischemic injury." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 22, Issue 6, pp. 631-47, (2002) (PubMed).
: "Head-to-head juxtaposition of Fas-associated phosphatase-1 (FAP-1) and c-Jun NH2-terminal kinase 3 (JNK3) genes: genomic structure and seven polymorphisms of the FAP-1 gene." in: Journal of human genetics, Vol. 47, Issue 11, pp. 614-9, (2002) (PubMed).
: "Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3." in: The EMBO journal, Vol. 21, Issue 3, pp. 324-33, (2002) (PubMed).
: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).
: "Mitogen-activated protein kinase kinase 4 (MKK4)." in: The international journal of biochemistry & cell biology, Vol. 32, Issue 6, pp. 581-7, (2000) (PubMed).
: "Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3." in: Science (New York, N.Y.), Vol. 290, Issue 5496, pp. 1574-7, (2000) (PubMed).
: "The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development." in: Neuron, Vol. 22, Issue 4, pp. 667-76, (1999) (PubMed).
Aliases for MAPK10 抗体
mitogen-activated protein kinase 8 S homeolog (mapk8.S) 抗体mitogen-activated protein kinase 10 (MAPK10) 抗体
mitogen-activated protein kinase 10 (mapk10) 抗体
mitogen activated protein kinase 10 (Mapk10) 抗体
mitogen-activated protein kinase 10 (Mapk10) 抗体
MAP kinase 10 (MPK10) 抗体
ATMPK10 抗体
C230008H04Rik 抗体
DKFZp459H0638 抗体
Jnk3 抗体
JNK3 抗体
JNK3A 抗体
JNK3B1 抗体
JNK3B2 抗体
MAPK10 抗体
MAP kinase 10 抗体
p54bSAPK 抗体
p493F12 抗体
PRKM10 抗体
SAPb 抗体
SAPK(beta) 抗体
SAPK1b 抗体
SAPKC 抗体
Serk2 抗体
zgc:123234 抗体
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