我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

MAP3K4 蛋白

(Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))

The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors. This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1. This protein contains a protein kinase catalytic domain at the C terminus. The N-terminal nonkinase domain may contain a regulatory domain. Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways, but not the ERK pathway. In vitro kinase studies indicated that recombinant MEKK4 can specifically phosphorylate and activate PRKMK6 and SERK1, MAPKKs that activate CSBP2 and JNK, respectively but cannot phosphorylate PRKMK1, an MAPKK that activates ERKs. MEKK4 is a major mediator of environmental stresses that activate the CSBP2 MAPK pathway, and a minor mediator of the JNK pathway. Two alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

recommended

MAP3K4 Protein (AA 1201-1300) (GST tag) (ABIN1310218)

MAP3K4 宿主: 人宿主: 小麦胚 Recombinant WB, AP, AA, ELISA

显示详细信息

recommended

MAP3K4 蛋白 (ABIN2750508)

MAP3K4 宿主: 人, 小鼠, 大鼠宿主: 大肠杆菌（E. Coli） Recombinant WB, PC

显示详细信息

MAP3K4 蛋白 by Origin

Find MAP3K4 蛋白 for a variety of species such as anti-Human MAP3K4, anti-Mouse MAP3K4, anti-Rat MAP3K4. The species listed below are among those available. Click on a link to go to the corresponding products.

MAP3K4 蛋白 by Source

Here you will find MAP3K4 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MAP3K4 蛋白 by 蛋白类型

Here you can find MAP3K4 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

MAP3K4 蛋白 by 应用范围

Find MAP3K4 蛋白 validated for a specific application such as WB, AP, AA, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MAP3K4 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MAP3K4 Protein (AA 1201-1300) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310218

Quantity 10 μg

Datasheet Datasheet

MAP3K4 蛋白

Reactivity Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2750508

Quantity 5 applications

Datasheet Datasheet

Aliases for MAP3K4 蛋白

mitogen activated protein kinase kinase kinase 4 (Map3k4) 蛋白
mitogen-activated protein kinase kinase kinase 4 (MAP3K4) 蛋白
mitogen-activated protein kinase kinase kinase 4 (Map3k4) 蛋白
D17Rp17 蛋白
D17Rp17e 蛋白
MAPKKK4 蛋白
Mek4b 蛋白
MEKK4 蛋白
MEKK 4 蛋白
Mekk4 蛋白
mKIAA0213 蛋白
MTK1 蛋白
PRO0412 蛋白
RP17 蛋白
Rp17a 蛋白
Tas 蛋白

您还需要查找其他产品吗？

You are here:

MAP3K4 蛋白 by Origin

MAP3K4 蛋白 by Source

MAP3K4 蛋白 by 蛋白类型

MAP3K4 蛋白 by 应用范围

Popular MAP3K4 蛋白

Aliases for MAP3K4 蛋白

您还需要查找其他产品吗？

antibodies-online

genomics-online