MAP2K3 抗体
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
MAP2K3 适用: 人, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D3 unconjugated
recommended
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Popular MAP2K3 抗体
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Cat. No.
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Application
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Cat. No.
ABIN6143484
Quantity
100 μL
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Dog, Human, Monkey, Mouse
Application
WB, IHC, IF, IHC (p)
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Cat. No.
ABIN1499401
Quantity
100 μL
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WB, IHC, IF, IHC (p)
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Cat. No.
ABIN1499403
Quantity
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Cat. No.
ABIN5542528
Quantity
100 μL
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Cat. No.
ABIN562427
Quantity
100 μg
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Datasheet
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Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IF, IHC (p)
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Cat. No.
ABIN1499400
Quantity
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Cat. No.
ABIN7138459
Quantity
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Cat. No.
ABIN6243255
Quantity
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WB, IHC, ELISA, IF, ICC
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Cat. No.
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Cat. No.
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WB, IHC, IF, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
ABIN7150707
Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Quantity
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Datasheet
Datasheet
Latest Publications for our MAP2K3 抗体
: "Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 768-781, (2018) (PubMed).: "MAPK kinase 10.2 promotes disease resistance and drought tolerance by activating different MAPKs in rice." in: The Plant journal : for cell and molecular biology, Vol. 92, Issue 4, pp. 557-570, (2018) (PubMed).
: "MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3." in: BMC cancer, Vol. 13, pp. 469, (2013) (PubMed).
: "MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival." in: Molecular cancer therapeutics, Vol. 6, Issue 4, pp. 1212-22, (2007) (PubMed).
: "Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4217-27, (2007) (PubMed).
: "Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase ..." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 529-44, (2003) (PubMed).
: "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38." in: Oncogene, Vol. 22, Issue 40, pp. 6129-41, (2003) (PubMed).
: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, (2002) (PubMed).
Aliases for MAP2K3 抗体
mitogen-activated protein kinase kinase 3 (MAP2K3) 抗体mitogen-activated protein kinase kinase 3 (Map2k3) 抗体
mitogen activated protein kinase kinase 3 (Map2k3) 抗体
MAP kinase activator XMEK3 (map2k3) 抗体
AW212142 抗体
MAPKK3 抗体
MEK3 抗体
MKK3 抗体
Mkk3 抗体
mMKK3b 抗体
PRKMK3 抗体
Prkmk3 抗体
SAPKK-2 抗体
SAPKK2 抗体
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