MAK 产品
(Male Germ Cell-Associated Kinase (MAK))
Categories
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].
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Featured MAK Categories
MAK 抗体
High quality antibodies with extensive validation data.
MAK ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MAK 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (6)
Cat. No.
ABIN517720
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7268382
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7169063
Quantity
100 μg
Datasheet
Datasheet
Recommended MAK ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381289
Quantity
96 tests
Datasheet
Datasheet
Recommended MAK 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310104
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310103
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508993
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MAK Products
: "Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice." in: Cytoskeleton (Hoboken, N.J.), (2015) (PubMed).: "Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E569-76, (2011) (PubMed).
: "Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells." in: Cancer research, Vol. 66, Issue 17, pp. 8439-47, (2006) (PubMed).
: "Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8639-54, (2006) (PubMed).
: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).
: "Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 35422-33, (2002) (PubMed).
: "Sterically stabilized liposomes: physical and biological properties." in: Journal of drug targeting, Vol. 2, Issue 5, pp. 397-403, (1995) (PubMed).
Synonyms and alternative names related to MAK
male germ cell associated kinase (MAK), male germ cell-associated kinase (Mak), male germ cell-associated kinase (mak), male germ cell associated kinase L homeolog (mak.L), male germ cell associated kinase (mak), A930010O05Rik, dJ417M14.2, fj04c02, Ick, MGC82717, MGC146434, RP62, rp62, wu:fj04c02, xmak, zgc:56603Protein level used designations for MAK
- male germ cell-associated kinase retinal-enriched isoform
- serine/threonine protein kinase MAK
- serine/threonine-protein kinase MAK
- protein kinase RCK
- intestinal cell kinase
- male germ cell-associated kinase
- serine/threonine-protein kinase MAK-like
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