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Major Basic Protein 产品

(Major Basic Protein)

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The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008].

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Featured Major Basic Protein Categories

Major Basic Protein 抗体

High quality antibodies with extensive validation data.

Major Basic Protein 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Major Basic Protein 抗体

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Cat. No. ABIN7428050
Quantity 100 μL
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Cat. No. ABIN7429931
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Cat. No. ABIN7426883
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Recommended Major Basic Protein ELISA试剂盒

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Reactivity
Analytical Method
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Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6720571
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Recommended Major Basic Protein 蛋白

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Reactivity
Source
Validations
Cat. No.
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Source Escherichia coli (E. coli)
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Quantity 100 μg
Datasheet Datasheet
Reactivity Human
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Cat. No. ABIN7394495
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Reactivity Rat
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Latest Publications for our Major Basic Protein Products

Sakai-Kashiwabara, Asano: "Inhibitory action of quercetin on eosinophil activation in vitro." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2013, pp. 127105, (2013) (PubMed).

Kingsnorth: "Ornithine decarboxylase as a marker for colorectal adenomas." in: The British journal of surgery, Vol. 74, Issue 11, pp. 1066, (1988) (PubMed).

Synonyms and alternative names related to Major Basic Protein

myelin basic protein (MBP), proteoglycan 2, bone marrow (Prg2), MBP, mMBP, mMBP-1

Protein level used designations for Major Basic Protein

  • myelin A1 protein
  • myelin membrane encephalitogenic protein
  • BMPG
  • bone marrow proteoglycan
  • major basic protein 1
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