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CD160 (human): 293T Lysate

CD160 WB Whole Cell Lysate Overexpression Lysate HEK 293T Cells
产品编号 ABIN1112255
发货至: 中国
  • 抗原 See all CD160 products
    CD160
    资源
    人细胞
    应用范围
    Western Blotting (WB)
    产品特性
    CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol- anchored protein of 181 amino acids with a single Ig- like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. Lysate of human CD160 transfected 293T cells
    Lysed Cells
    HEK 293T Cells
    Lysate Type
    Overexpression Lysate
    Lysate Fraction
    Whole Cell Lysate
  • 应用备注
    CD160 (h): 293T Lysate is suitable as a Western Blotting positive control for human reactive CD160 antibodies. Recommended use: 10-20 µl per lane. Control 293T Lysate: 293LYS is available as a Western Blotting negative control lysate derived from non-transfected 293T cells.
    限制
    仅限研究用
  • 注意事项
    Repeated freezing and thawing should be minimized. Sample vial should be boiled once prior to use. Non-hazardous. No MSDS required.
    储存条件
    -20 °C
  • Edwards, Durant, Jones, Evans, Smith: "Differential expression of HLA class II antigens in fetal human spleen: relationship of HLA-DP, DQ, and DR to immunoglobulin expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 137, Issue 2, pp. 490-7, (1986) (PubMed).

    Austin, Trowsdale, Rudd, Bodmer, Feldmann, Lamb: "Functional expression of HLA-DP genes transfected into mouse fibroblasts." in: Nature, Vol. 313, Issue 5997, pp. 61-4, (1985) (PubMed).

    Royston, Omary, Trowbridge: "Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia." in: Transplantation proceedings, Vol. 13, Issue 1 Pt 2, pp. 761-6, (1981) (PubMed).

  • 抗原
    CD160
    别名
    CD160 (CD160 产品)
    别名
    CD160 Lysate, RGD1563598 Lysate, BY55 Lysate, AU045688 Lysate, By55 Lysate, NK1 Lysate, NK28 Lysate, CD160 molecule Lysate, CD160 antigen Lysate, CD160 Lysate, Cd160 Lysate
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