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Lysine (K)-Specific Demethylase 1A 产品

(Lysine (K)-Specific Demethylase 1A (KDM1A))

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This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

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Featured Lysine (K)-Specific Demethylase 1A Categories

Lysine (K)-Specific Demethylase 1A 抗体

High quality antibodies with extensive validation data.

Lysine (K)-Specific Demethylase 1A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Lysine (K)-Specific Demethylase 1A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Lysine (K)-Specific Demethylase 1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (7)
Cat. No. ABIN3021575
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7268323
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN7193459
Quantity 100 μL
Datasheet Datasheet

Recommended Lysine (K)-Specific Demethylase 1A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (3)
Cat. No. ABIN6730574
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968387
Quantity 96 tests
Datasheet Datasheet

Recommended Lysine (K)-Specific Demethylase 1A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345223
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345221
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus
Validations
  • (2)
Cat. No. ABIN2669678
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Lysine (K)-Specific Demethylase 1A Products

Haydn, Kehr, Willmann, Metzger, Schüle, Fulda: "Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells." in: International journal of cancer, (2019) (PubMed).

Kim, Nam, Lee, Yim, Ahn, Park, Shin, Yu, Won, Bae, Kim, Baek: "PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response." in: Molecular cell, Vol. 69, Issue 3, pp. 398-411.e6, (2018) (PubMed).

Lobo, Rodrigues, Antunes, Graça, Ramalho-Carvalho, Vieira, Martins, Oliveira, Jerónimo, Henrique: "High immunoexpression of Ki67, EZH2, and SMYD3 in diagnostic prostate biopsies independently predicts outcome in patients with prostate cancer." in: Urologic oncology, (2017) (PubMed).

Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).

Pérez-Cerezales, Ramos-Ibeas, Lopez-Cardona, Pericuesta, Fernandez-Gonzalez, Pintado, Gutiérrez-Adán: "Elimination of methylation marks at lysines 4 and 9 of histone 3 (H3K4 and H3K9) of spermatozoa alters offspring phenotype." in: Reproduction, fertility, and development, (2015) (PubMed).

Periz, Lu, Zhang, Kankel, Jablonski, Kalb, McCampbell, Wang: "Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription." in: PLoS biology, Vol. 13, Issue 4, pp. e1002114, (2015) (PubMed).

Boxer, Barajas, Tao, Zhang, Khavari: "ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes." in: Genes & development, Vol. 28, Issue 18, pp. 2013-26, (2014) (PubMed).

Huang, Li, Song, Li, Li, Zhang, Han, Zhang, Miao, Du, Wang: "Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/?-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected]." in: PLoS ONE, Vol. 8, Issue 7, pp. e70077, (2013) (PubMed).

Kashyap, Ahmad, Nilsson, Helczynski, Kenna, Persson, Gudas, Mongan: "The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer." in: Molecular oncology, Vol. 7, Issue 3, pp. 555-66, (2013) (PubMed).

Pajtler, Weingarten, Thor, Künkele, Heukamp, Büttner, Suzuki, Miyata, Grotzer, Rieb, Sprüssel, Eggert, Schramm, Schulte: "The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma." in: Acta neuropathologica communications, Vol. 1, pp. 19, (2013) (PubMed).

Synonyms and alternative names related to Lysine (K)-Specific Demethylase 1A

lysine demethylase 1A (KDM1A), lysine (K)-specific demethylase 1A (Kdm1a), lysine demethylase 1A (Kdm1a), lysine (K)-specific demethylase 1a (kdm1a), lysine (K)-specific demethylase 1A (kdm1a), lysine demethylase 1A (kdm1a), LSD1 zinc finger family protein (LSD1), 1810043O07Rik, AA408884, AOF2, Aof2, aof2, AtLSD1, BHC110, D4Ertd478e, DKFZp459N2450, F9F13.30, F9F13_30, KDM1, Kdm1, kdm1, KDM1A, LESION SIMULATING DISEASE, LESION SIMULATING DISEASE 1, LSD1, Lsd1, lsd1, mKIAA0601, RGD1562975, wu:fb82e06, wu:fc51a02, wu:fj36a05, wu:fj66b06, xLSD1

Protein level used designations for Lysine (K)-Specific Demethylase 1A

  • BRAF35-HDAC complex protein BHC110
  • FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit
  • amine oxidase (flavin containing) domain 2
  • flavin-containing amine oxidase domain-containing protein 2
  • lysine (K)-specific demethylase 1
  • lysine-specific histone demethylase 1
  • lysine-specific histone demethylase 1A
  • neuroprotective protein 3
  • lsd1
  • lysine (K)-specific demethylase 1A
  • Protein CHILLING SENSITIVE 4
  • Protein LESION SIMULATING DISEASE 1
  • Putative zinc finger LSD1
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