LRRC8A 产品
(Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured LRRC8A Categories
Recommended LRRC8A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, FACS, IF
Validations
- (4)
Cat. No.
ABIN7043301
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN1327159
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
- (2)
Cat. No.
ABIN1881512
Quantity
400 μL
Datasheet
Datasheet
Recommended LRRC8A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309795
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3116341
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136050
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our LRRC8A Products
: "LRRC8 extracellular domain is composed of 17 leucine-rich repeats." in: Molecular immunology, Vol. 41, Issue 5, pp. 561-2, (2004) (PubMed).: "Genes required for B cell development." in: The Journal of clinical investigation, Vol. 112, Issue 11, pp. 1636-8, (2003) (PubMed).
Synonyms and alternative names related to LRRC8A
leucine rich repeat containing 8 VRAC subunit A (LRRC8A), leucine rich repeat containing 8A (Lrrc8a), leucine rich repeat containing 8 VRAC subunit A (Lrrc8a), leucine rich repeat containing 8 VRAC subunit Aa (lrrc8aa), leucine-rich repeat containing 8 family member A S homeolog (lrrc8a.S), leucine rich repeat containing 8 family member A (LRRC8A), AGM5, LLRC8A, LRRC8, Lrrc8, mKIAA1437, wu:fb18g12, wu:fi21b10Protein level used designations for LRRC8A
- leucine-rich repeat-containing protein 8A
- leucine-rich repeat-containing 8
- leucine rich repeat containing 8A
- leucine rich repeat containing 8 family member A
- volume-regulated anion channel subunit LRRC8A
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