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LRP2 蛋白

(Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))

The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling\; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].

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LRP2 Protein (AA 4035-4184) (His tag) (ABIN7397174)

LRP2 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, Imm, PC

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recommended

LRP2 Protein (AA 1186-1389, Extracellular) (His tag) (ABIN5713618)

LRP2 宿主: 人宿主: 酵母菌 Recombinant > 90 % SDS

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LRP2 蛋白 by Origin

Find LRP2 蛋白 for a variety of species such as anti-Human LRP2. The species listed below are among those available. Click on a link to go to the corresponding products.

LRP2 蛋白 by Source

Here you will find LRP2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

LRP2 蛋白 by 蛋白类型

Here you can find LRP2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

LRP2 蛋白 by 应用范围

Find LRP2 蛋白 validated for a specific application such as SDS, Imm, PC, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular LRP2 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

LRP2 Protein (AA 4035-4184) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397174

Quantity 100 μg

Datasheet Datasheet

LRP2 Protein (AA 1186-1389, Extracellular) (His tag)

Reactivity Human

Source Yeast

Validations

Cat. No. ABIN5713618

Quantity 100 μg

Datasheet Datasheet

Aliases for LRP2 蛋白

LDL receptor related protein 2 (LRP2) 蛋白
low density lipoprotein receptor-related protein 2a (lrp2a) 蛋白
low density lipoprotein receptor-related protein 2 (LRP2) 蛋白
low-density lipoprotein receptor-related protein 2 (LRP2.3) 蛋白
LDL receptor related protein 2 L homeolog (lrp2.L) 蛋白
low-density lipoprotein receptor-related protein 2 (LOC100183506) 蛋白
LDL receptor related protein 2 (lrp2) 蛋白
low density lipoprotein receptor-related protein 2 (Lrp2) 蛋白
LDL receptor related protein 2 (Lrp2) 蛋白
AI315343 蛋白
AW536255 蛋白
D230004K18Rik 蛋白
dbs 蛋白
DBS 蛋白
gp330 蛋白
GP330 蛋白
Gp330 蛋白
im:680590 蛋白
lrp2 蛋白
megalin 蛋白
Megalin 蛋白

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LRP2 蛋白 by Origin

LRP2 蛋白 by Source

LRP2 蛋白 by 蛋白类型

LRP2 蛋白 by 应用范围

Popular LRP2 蛋白

Aliases for LRP2 蛋白

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