LRP2 抗体
(Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling\; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].
recommended
recommended
LRP2 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
LRP2 抗体 by 适用
Find LRP2 抗体 for a variety of species such as anti-Human LRP2, anti-Mouse LRP2, anti-Rat LRP2. The species listed below are among those available. Click on a link to go to the corresponding products.
LRP2 抗体 by 应用范围
Find LRP2 抗体 validated for a specific application such as ELISA, IHC, FACS, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.
LRP2 抗体 by 抗体来源
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LRP2 抗体 by 抗原表位
Find LRP2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
LRP2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal LRP2 抗体. Click on a link to go to the corresponding products.
LRP2 抗体 by 克隆
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Popular LRP2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
FACS, IF (cc), IF (p)
Validations
- (1)
Cat. No.
ABIN750991
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (2)
- (4)
Cat. No.
ABIN750988
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7158571
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (2)
Cat. No.
ABIN7435346
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (2)
Cat. No.
ABIN7074514
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB
Validations
- (2)
Cat. No.
ABIN1680712
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
FACS
Validations
- (1)
Cat. No.
ABIN750998
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7158567
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7238111
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC, WB
Validations
- (1)
Cat. No.
ABIN6263006
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN3031639
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN750990
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN905128
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN2803846
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN905130
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our LRP2 抗体
: "Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension." in: Journal of the American Heart Association, Vol. 8, Issue 8, pp. e012395, (2019) (PubMed).: "IL-6/Smad2 signaling mediates acute kidney injury and regeneration in a murine model of neonatal hyperoxia." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 5887-5902, (2019) (PubMed).
: "Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule." in: International journal of molecular sciences, Vol. 20, Issue 10, (2019) (PubMed).
: "A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells." in: Stem cell reports, Vol. 11, Issue 2, pp. 470-484, (2018) (PubMed).
: "Combined Structural and Functional Imaging of the Kidney Reveals Major Axial Differences in Proximal Tubule Endocytosis." in: Journal of the American Society of Nephrology : JASN, Vol. 29, Issue 11, pp. 2696-2712, (2018) (PubMed).
: "Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism." in: Cellular and molecular life sciences : CMLS, Vol. 75, Issue 21, pp. 4021-4040, (2018) (PubMed).
: "Human extravillous trophoblasts bind but do not internalize antiphospholipid antibodies." in: Placenta, Vol. 42, pp. 9-16, (2016) (PubMed).
: "Role of serotonin in the regulation of renal proximal tubular epithelial cells." in: Renal failure, Vol. 38, Issue 7, pp. 1141-50, (2016) (PubMed).
: "Rho GAP myosin IXa is a regulator of kidney tubule function." in: American journal of physiology. Renal physiology, Vol. 309, Issue 6, pp. F501-13, (2015) (PubMed).
: "Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway." in: Oncology reports, Vol. 34, Issue 5, pp. 2251-8, (2015) (PubMed).
Aliases for LRP2 抗体
LDL receptor related protein 2 (LRP2) 抗体low density lipoprotein receptor-related protein 2a (lrp2a) 抗体
low density lipoprotein receptor-related protein 2 (LRP2) 抗体
low-density lipoprotein receptor-related protein 2 (LRP2.3) 抗体
LDL receptor related protein 2 L homeolog (lrp2.L) 抗体
low-density lipoprotein receptor-related protein 2 (LOC100183506) 抗体
LDL receptor related protein 2 (lrp2) 抗体
low density lipoprotein receptor-related protein 2 (Lrp2) 抗体
LDL receptor related protein 2 (Lrp2) 抗体
AI315343 抗体
AW536255 抗体
D230004K18Rik 抗体
dbs 抗体
DBS 抗体
gp330 抗体
GP330 抗体
Gp330 抗体
im:680590 抗体
lrp2 抗体
megalin 抗体
Megalin 抗体
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