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Lysophosphatidic Acid Receptor 1 产品

(Lysophosphatidic Acid Receptor 1 (LPAR1))

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The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008].

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Featured Lysophosphatidic Acid Receptor 1 Categories

Lysophosphatidic Acid Receptor 1 抗体

High quality antibodies with extensive validation data.

Lysophosphatidic Acid Receptor 1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Lysophosphatidic Acid Receptor 1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Lysophosphatidic Acid Receptor 1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (p), IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN681103
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
Cat. No. ABIN1499191
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7188716
Quantity 100 μg
Datasheet Datasheet

Recommended Lysophosphatidic Acid Receptor 1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968389
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957579
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1573809
Quantity 96 tests
Datasheet Datasheet

Recommended Lysophosphatidic Acid Receptor 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309682
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309681
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396538
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Lysophosphatidic Acid Receptor 1 Products

Harper, Brochu-Gaudreau, Saucier, Dubois: "Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion." in: Cancers, Vol. 11, Issue 9, (2019) (PubMed).

Chen, Zhang, Deng, Liu, Yang, Wu, Yu: "Lysophosphatidic acid directly induces macrophage-derived foam cell formation by blocking the expression of SRBI." in: Biochemical and biophysical research communications, Vol. 491, Issue 3, pp. 587-594, (2017) (PubMed).

Wu, Yuan, Wang, Wei, Xu: "Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats." in: Molecular pain, Vol. 12, (2016) (PubMed).

Mori, Araki, Ishii, Hirane, Fukushima, Tomimatsu, Takahashi, Fukushima, Tsujiuchi: "LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs." in: Molecular and cellular biochemistry, Vol. 408, Issue 1-2, pp. 147-54, (2015) (PubMed).

Hirane, Ishii, Tomimatsu, Fukushima, Takahashi, Fukushima, Honoki, Tsujiuchi: "Different induction of LPA receptors by chemical liver carcinogens regulates cellular functions of liver epithelial WB-F344 cells." in: Molecular carcinogenesis, Vol. 55, Issue 11, pp. 1573-1583, (2015) (PubMed).

Sokolov, Eheim, Ahrens, Walling, Swet, McMillan, Simo, Thompson, Sindram, McKillop: "Lysophosphatidic acid receptor expression and function in human hepatocellular carcinoma." in: The Journal of surgical research, Vol. 180, Issue 1, pp. 104-13, (2013) (PubMed).

Arriazu, Durán, Pozuelo, Santamaria: "Expression of lysophosphatidic acid receptor 1 and relation with cell proliferation, apoptosis, and angiogenesis on preneoplastic changes induced by cadmium chloride in the rat ventral prostate." in: PLoS ONE, Vol. 8, Issue 2, pp. e57742, (2013) (PubMed).

Wei, Johansson, Chen, Song, Tolman, Li, Hurd, Patidar, Wen, Badgett, Cheuk, Marshall, Steeg, Vaqué Díez, Yu, Gutkind, Khan: "Massively parallel sequencing reveals an accumulation of de novo mutations and an activating mutation of LPAR1 in a patient with metastatic neuroblastoma." in: PLoS ONE, Vol. 8, Issue 10, pp. e77731, (2013) (PubMed).

Park, Kazlauskas: "Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA)." in: Bioscience reports, Vol. 32, Issue 4, pp. 393-400, (2012) (PubMed).

Ward, Lake, Yin, Heger, Raffeld, Goldsmith, Merino, Kelly: "LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells." in: Cancer research, Vol. 71, Issue 23, pp. 7301-11, (2011) (PubMed).

Synonyms and alternative names related to Lysophosphatidic Acid Receptor 1

lysophosphatidic acid receptor 1 (LPAR1), lysophosphatidic acid receptor 1 (Lpar1), lysophosphatidic acid receptor 1 (lpar1), lysophosphatidic acid receptor 1 S homeolog (lpar1.S), lysophosphatidic acid receptor 1 L homeolog (lpar1.L), 5031439C20, AI326300, edg-2, EDG-2, EDG2, Edg2, edg2, edg2-A, Gpcr26, GPR26, gpr26, Kdt2, LPA-1-A, LPA-1-B, LPA1, lpA1, lpa1, lpa1r, lpa1r1, lpar1, lpar1-a, lpar1-b, LPA receptor 1-A, LPA receptor 1-B, Mrec1.3, rec.1.3, si:dz22b13.1, si:dz46m7.1, vzg-1, VZG1, vzg1, xLPA1-1, xLPA1-2, xlpa1R, zgc:92157

Protein level used designations for Lysophosphatidic Acid Receptor 1

  • LPA receptor 1
  • LPA-1
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
  • lysophosphatidic acid receptor Edg-2
  • ventricular zone gene 1
  • rec1.3
  • lysophosphatidic acid receptor 1
  • lysophosphatidic acid receptor 1-like
  • endothelium differentiation gene 2
  • G-protein coupled receptor 26
  • clone 4.9
  • endothelial differentiation lysophosphatidic acid G-protein-coupled receptor 2
  • lpa1
  • zlpa1
  • LPA receptor 1-A
  • LPA-1-A
  • Lysophosphatidic acid receptor LPA1 homolog 1
  • lysophosphatidic acid receptor 1-A
  • lysophosphatidic acid receptor LPA1 homolog 1
  • xLPA1-1
  • LPA receptor 1-B
  • LPA-1-B
  • Lysophosphatidic acid receptor LPA1 homolog 2
  • lysophosphatidic acid G-protein-coupled receptor 2
  • lysophosphatidic acid receptor 1-B
  • lysophosphatidic acid receptor LPA1 homolog 2
  • xLPA1-2
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