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LONP1 抗体

(Lon Peptidase 1, Mitochondrial (LONP1))
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013].
LONP1 抗体  (AA 361-460) LONP1 抗体  (AA 361-460) LONP1 抗体 (AA 361-460) (ABIN705806)

LONP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

LONP1 抗体  (AA 1-959) LONP1 抗体  (AA 1-959) LONP1 抗体 (AA 1-959) (ABIN522820)

LONP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

LONP1 抗体  (AA 120-400) LONP1 抗体  (AA 120-400) LONP1 抗体 (AA 120-400) (ABIN1680707)

LONP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

LONP1 抗体 by 适用

Find LONP1 抗体 for a variety of species such as anti-Human LONP1, anti-Mouse LONP1, anti-Rat LONP1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find LONP1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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LONP1 抗体 by 抗原表位

Find LONP1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LONP1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal LONP1 抗体. Click on a link to go to the corresponding products.

LONP1 抗体 by 克隆

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LONP1 抗体 by 标记

Find LONP1 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LONP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (5)
Cat. No. ABIN705806
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN522820
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (4)
Cat. No. ABIN1680707
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6262995
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7158488
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (5)
  • (2)
Cat. No. ABIN1881504
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN522821
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN705808
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN905012
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN905013
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN5006248
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN905015
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN905014
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN5006247
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN2803812
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our LONP1 抗体

Ishikawa, Kobayashi, Yamada, Umehara, Oka, Nakada: "Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells." in: PLoS ONE, Vol. 14, Issue 3, pp. e0213283, (2019) (PubMed).

Sekine, Wang, Sideris, Bunker, Zhang, Youle: "Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1." in: Molecular cell, Vol. 73, Issue 5, pp. 1028-1043.e5, (2019) (PubMed).

Pareek, Thomas, Pallanck: "Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration." in: Cell death & disease, Vol. 9, Issue 3, pp. 304, (2018) (PubMed).

Boutoual, Meseguer, Villarroya, Martín-Hernández, Errami, Martín, Casado, Armengod: "Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis." in: Scientific reports, Vol. 8, Issue 1, pp. 1163, (2018) (PubMed).

Pareek, Thomas, Vincow, Morris, Pallanck: "Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation." in: Cell death discovery, Vol. 4, pp. 51, (2018) (PubMed).

Thomas, Andrews, Burman, Lin, Pallanck: "PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix." in: PLoS genetics, Vol. 10, Issue 5, pp. e1004279, (2014) (PubMed).

Jin, Youle: "The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria." in: Autophagy, Vol. 9, Issue 11, pp. 1750-7, (2013) (PubMed).

Merra, Lago, Ricci, Antuzzi, Gasbarrini, Gasbarrini, Ghirlanda: "Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman." in: Case reports in gastroenterology, Vol. 2, Issue 3, pp. 474-8, (2011) (PubMed).

Gozal, Duong, Gearing, Cheng, Hanfelt, Funderburk, Peng, Lah, Levey: "Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease." in: Journal of proteome research, Vol. 8, Issue 11, pp. 5069-79, (2009) (PubMed).

Chen, Suzuki, Wu: "Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA." in: Nucleic acids research, Vol. 36, Issue 4, pp. 1273-87, (2008) (PubMed).

Aliases for LONP1 抗体

lon peptidase 1, mitochondrial (LONP1) 抗体
lon peptidase 1, mitochondrial (lonp1) 抗体
lon peptidase 1, mitochondrial (Lonp1) 抗体
ATP-dependent Lon protease (PIM1) 抗体
1200017E13Rik 抗体
fc64d11 抗体
hLON 抗体
LON 抗体
Lon 抗体
LonHS 抗体
LONP 抗体
PIM1 抗体
PRSS15 抗体
prss15 抗体
Prss15 抗体
wu:fc64d11 抗体
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