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LITAF 抗体

(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008].
LITAF 抗体  (AA 1-161) LITAF 抗体  (AA 1-161) LITAF 抗体 (AA 1-161) (ABIN523000)

LITAF 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

LITAF 抗体  (AA 1-161) LITAF 抗体  (AA 1-161) LITAF 抗体 (AA 1-161) (ABIN7158438)

LITAF 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

LITAF 抗体 LITAF 抗体 LITAF 抗体 (ABIN7074508)

LITAF 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

LITAF 抗体 by Grade

Find LITAF 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

LITAF 抗体 by 适用

Find LITAF 抗体 for a variety of species such as anti-Human LITAF, anti-Mouse LITAF, anti-Rat LITAF. The species listed below are among those available. Click on a link to go to the corresponding products.

LITAF 抗体 by 应用范围

Find LITAF 抗体 validated for a specific application such as WB, IHC, IF, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LITAF 抗体 by 抗体来源

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LITAF 抗体 by 抗原表位

Find LITAF 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LITAF 抗体 by 克隆形成能力

Find available monoclonal or polyclonal LITAF 抗体. Click on a link to go to the corresponding products.

LITAF 抗体 by 克隆

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LITAF 抗体 by 标记

Find LITAF 抗体 with a specific conjugate such as Biotin, APC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LITAF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN523000
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7158438
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7074508
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN7261431
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (3)
Cat. No. ABIN6143254
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN523001
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN6262981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1804269
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, IHC (p), ChIP-seq
Validations
  • (2)
Cat. No. ABIN2856656
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243247
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN948817
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN238579
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7307980
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, EIA
Validations
  • (2)
Cat. No. ABIN371885
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IP, IHC (p)
Validations
Cat. No. ABIN6989826
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our LITAF 抗体

Zhu, Guariglia, Yu, Li, Brancho, Peinado, Lyden, Salzer, Bennett, Chow: "Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes." in: Molecular biology of the cell, Vol. 24, Issue 11, pp. 1619-37, S1-3, (2013) (PubMed).

Tang, Metzger, Leeman, Amar: "LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 37, pp. 13777-82, (2006) (PubMed).

Saifi, Szigeti, Wiszniewski, Shy, Krajewski, Hausmanowa-Petrusewicz, Kochanski, Reeser, Mancias, Butler, Lupski: "SIMPLE mutations in Charcot-Marie-Tooth disease and the potential role of its protein product in protein degradation." in: Human mutation, Vol. 25, Issue 4, pp. 372-83, (2005) (PubMed).

Moriwaki, Begum, Kobayashi, Matsumoto, Toyoshima, Seya: "Mycobacterium bovis Bacillus Calmette-Guerin and its cell wall complex induce a novel lysosomal membrane protein, SIMPLE, that bridges the missing link between lipopolysaccharide and p53-inducible gene, LITAF(PIG7), and estrogen-inducible gene, EET-1." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 23065-76, (2001) (PubMed).

Myokai, Takashiba, Lebo, Amar: "A novel lipopolysaccharide-induced transcription factor regulating tumor necrosis factor alpha gene expression: molecular cloning, sequencing, characterization, and chromosomal assignment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4518-23, (1999) (PubMed).

Aliases for LITAF 抗体

lipopolysaccharide induced TNF factor (LITAF) 抗体
lipopolysaccharide-induced TNF factor (Litaf) 抗体
LPS-induced TN factor (Litaf) 抗体
3222402J11Rik 抗体
C85531 抗体
EET-1 抗体
N4WBP3 抗体
PIG7 抗体
Pig7 抗体
SIMPLE 抗体
TBX1 抗体
TNF-alpha 抗体
TP53I7 抗体
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