LIN28B 产品
(Lin-28 Homolog B (LIN28B))
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The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012].
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Featured LIN28B Categories
Recommended LIN28B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF
Validations
- (9)
Cat. No.
ABIN3031627
Quantity
0.2 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF
Validations
- (6)
Cat. No.
ABIN3031628
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7165750
Quantity
100 μg
Datasheet
Datasheet
Recommended LIN28B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229057
Quantity
96 tests
Datasheet
Datasheet
Recommended LIN28B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7123767
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our LIN28B Products
: "Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma." in: Blood, Vol. 120, Issue 5, pp. 1048-59, (2012) (PubMed).: "Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer." in: Molecular cancer research : MCR, Vol. 9, Issue 1, pp. 36-50, (2011) (PubMed).
: "IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2." in: Cancer research, Vol. 71, Issue 6, pp. 2172-82, (2011) (PubMed).
: "Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma." in: Gene, Vol. 384, pp. 51-61, (2006) (PubMed).
Synonyms and alternative names related to LIN28B
lin-28 homolog B (LIN28B), lin-28 homolog B (lin28b), lin-28 homolog B S homeolog (lin28b.S), lin-28 homolog B (C. elegans) (Lin28b), lin-28 homolog B (C. elegans) (LIN28B), lin-28 homolog B (Lin28b), 2810403D23Rik, csdd2, CSDD2, D030047M17Rik, LIN-28, Lin-28.2Protein level used designations for LIN28B
- lin-28 homolog B (C. elegans)
- lin-28 homolog B
- Lin-28.2
- lin-28B
- protein lin-28 homolog B
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