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LIMS1 产品

(LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

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Featured LIMS1 Categories

LIMS1 抗体

High quality antibodies with extensive validation data.

LIMS1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

LIMS1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LIMS1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, ICC
Validations
  • (2)
  • (5)
Cat. No. ABIN969354
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7158341
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7237326
Quantity 200 μL
Datasheet Datasheet

Recommended LIMS1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957478
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5656419
Quantity 96 tests
Datasheet Datasheet

Recommended LIMS1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309446
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309444
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405864
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LIMS1 Products

Yang, Wang, Hawkins, Chen, Vaynberg, Mao, Tu, Zuo, Wang, Wang, Wu, Tjandra, Qin: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).

Chiswell, Zhang, Murphy, Boggon, Calderwood: "The structural basis of integrin-linked kinase-PINCH interactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, (2008) (PubMed).

Campana, Myers, Rearden: "Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury." in: Glia, Vol. 41, Issue 3, pp. 213-23, (2003) (PubMed).

Tu, Li, Goicoechea, Wu: "The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells." in: Molecular and cellular biology, Vol. 19, Issue 3, pp. 2425-34, (1999) (PubMed).

Tu, Li, Wu: "Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways." in: Molecular biology of the cell, Vol. 9, Issue 12, pp. 3367-82, (1999) (PubMed).

Synonyms and alternative names related to LIMS1

LIM zinc finger domain containing 1 (LIMS1), LIM zinc finger domain containing 1 (Lims1), LIM and senescent cell antigen-like domains 1 (Lims1), 2310016J22Rik, 4921524A02Rik, AI507642, AU021743, AW551584, C430041B13Rik, Lims1l, LIMS3, LIMS3L, PINCH, PINCH-1, PINCH1, Pinch1, RGD1560732

Protein level used designations for LIMS1

  • LIM and senescent cell antigen-like-containing domain protein 1
  • particularly interesting new Cys-His protein 1
  • renal carcinoma antigen NY-REN-48
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