LIMD1 产品
(LIM Domains Containing 1 (LIMD1))
Categories
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG- dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1- responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation (By similarity).
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Featured LIMD1 Categories
Recommended LIMD1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (5)
Cat. No.
ABIN522438
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (5)
Cat. No.
ABIN2856419
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN6744453
Quantity
100 μL
Datasheet
Datasheet
Recommended LIMD1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309428
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309430
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093519
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to LIMD1
LIM domains containing 1 (LIMD1), LIM domains containing 1 (Limd1), LIM domains containing 1 (limd1), LIM domains containing 1 L homeolog (limd1.L), AW822033, D9Ertd192e, xlimd1Protein level used designations for LIMD1
- LIM domain-containing protein 1
- LIM domains-containing protein 1
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