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LIMA1 产品

(LIM Domain and Actin Binding 1 (LIMA1))

Categories

This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011].

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Featured LIMA1 Categories

LIMA1 抗体

High quality antibodies with extensive validation data.

LIMA1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LIMA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN526747
Quantity 100 μg
Datasheet Datasheet
Reactivity Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (3)
Cat. No. ABIN2776038
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN7255726
Quantity 200 μL
Datasheet Datasheet

Recommended LIMA1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228329
Quantity 96 tests
Datasheet Datasheet

Recommended LIMA1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309424
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our LIMA1 Products

Zhang, Wang, Iqbal, Wang, Osunkoya, Chen, Chen, Shin, Yuan, Wang, Zhau, Chung, Ritenour, Kucuk, Wu: "Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 288, Issue 3, pp. 1469-79, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Steder, Alla, Meier, Spitschak, Pahnke, Fürst, Kowtharapu, Engelmann, Petigk, Egberts, Schäd-Trcka, Gross, Nettelbeck, Niemetz, Pützer: "DNp73 exerts function in metastasis initiation by disconnecting the inhibitory role of EPLIN on IGF1R-AKT/STAT3 signaling." in: Cancer cell, Vol. 24, Issue 4, pp. 512-27, (2013) (PubMed).

Zhang, Wang, Osunkoya, Iqbal, Wang, Chen, Müller, Chen, Josson, Coleman, Nelson, Wang, Wang, Shin, Marshall, Kucuk, Chung, Zhau, Wu: "EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis." in: Oncogene, Vol. 30, Issue 50, pp. 4941-52, (2011) (PubMed).

Khositseth, Pisitkun, Slentz, Wang, Hoffert, Knepper, Yu: "Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 1, pp. M110.004036, (2011) (PubMed).

Han, Kosako, Watanabe, Hattori: "Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN." in: Molecular and cellular biology, Vol. 27, Issue 23, pp. 8190-204, (2007) (PubMed).

Maul, Song, Amann, Gerbin, Pollard, Chang: "EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).

Synonyms and alternative names related to LIMA1

LIM domain and actin binding 1 (Lima1), LIM domain and actin binding 1 (LIMA1), LIM domain and actin binding 1 (lima1), 1110021C24Rik, 3526402A12Rik, D15Ertd366e, eplin, EPLIN, Eplin, LIMA1, MGC146397, SREBP3

Protein level used designations for LIMA1

  • LIM domain and actin-binding protein 1
  • epithelial protein lost in neoplasm
  • LIM domain and actin binding 1
  • epithelial protein lost in neoplasm beta
  • 1110021C24Rik
  • sterol regulatory element binding protein 3
  • epithelial protein lost in neoplasm-a
  • epithelial protein lost in neoplasm-b
  • mEPLIN
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