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LIG4 ELISA试剂盒

(Ligase IV, DNA, ATP-Dependent (LIG4))

The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].

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LIG4 ELISA 试剂盒 (ABIN6216177)

LIG4 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum

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Popular LIG4 ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

LIG4 ELISA 试剂盒

Reactivity Human

Analytical Method Quantitative Sandwich ELISA

Validations

Cat. No. ABIN6216177

Quantity 96 tests

Datasheet Datasheet

Aliases for LIG4 ELISA试剂盒

ligase IV, DNA, ATP-dependent (lig4) ELISA试剂盒
DNA ligase 4 (LIG4) ELISA试剂盒
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