LIG1 产品
(Ligase I, DNA, ATP-Dependent (LIG1))
Categories
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq, Jul 2008].
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Featured LIG1 Categories
LIG1 抗体
High quality antibodies with extensive validation data.
LIG1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
LIG1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LIG1 抗体
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Recommended LIG1 ELISA试剂盒
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Recommended LIG1 蛋白
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Latest Publications for our LIG1 Products
: "DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).: "Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex." in: The EMBO journal, Vol. 34, Issue 13, pp. 1829-43, (2015) (PubMed).
: "Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity." in: Biochemistry, Vol. 50, Issue 11, pp. 1901-9, (2011) (PubMed).
: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).
: "Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity." in: Nucleic acids research, Vol. 37, Issue 10, pp. 3431-41, (2009) (PubMed).
: "Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks." in: Nucleic acids research, Vol. 36, Issue 10, pp. 3297-310, (2008) (PubMed).
: "Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells." in: The Journal of pharmacology and experimental therapeutics, Vol. 321, Issue 1, pp. 318-26, (2007) (PubMed).
: "A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22721-30, (2007) (PubMed).
: "Low levels of DNA ligases III and IV sufficient for effective NHEJ." in: Journal of cellular physiology, Vol. 213, Issue 2, pp. 475-83, (2007) (PubMed).
: "Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20865-72, (2006) (PubMed).
Synonyms and alternative names related to LIG1
DNA ligase 1 (LIG1), DNA ligase 1 (PB000674.02.0), DNA ligase 1 (PTRG_06243), DNA ligase 1, putative (PKH_140260), ligase I, DNA, ATP-dependent L homeolog (lig1.L), ligase I, DNA, ATP-dependent (Lig1), DNA ligase 1 (Lig1), DNA ligase 1 (lig-1), ligase I, DNA, ATP-dependent (lig1), AL033288, ATLIG1, DNA ligase 1, lig1, ligI, LigI, T6D22.23, wu:fc54a11Protein level used designations for LIG1
- DNA ligase 1
- polydeoxyribonucleotide synthase [ATP] 1
- DNA ligase (ATP) 1
- DNA ligase I
- LIG1, ligase I, DNA, ATP-dependent
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