LGMN 抗体
(Legumain (LGMN))
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
LGMN 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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Find LGMN 抗体 for a variety of species such as anti-Human LGMN, anti-Mouse LGMN, anti-Rat LGMN. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find available monoclonal or polyclonal LGMN 抗体. Click on a link to go to the corresponding products.
LGMN 抗体 by 克隆
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Popular LGMN 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
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Cat. No.
ABIN7435007
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7440881
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, FACS, IHC (p)
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- (5)
Cat. No.
ABIN750958
Quantity
100 μL
Datasheet
Datasheet
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Application
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Cat. No.
ABIN6143172
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
IF
Validations
- (3)
Cat. No.
ABIN7255373
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
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- (2)
Cat. No.
ABIN519319
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN519318
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN519317
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
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Cat. No.
ABIN7157971
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA
Validations
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- (1)
Cat. No.
ABIN562455
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1804571
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
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- (2)
Cat. No.
ABIN1881495
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IP
Validations
- (1)
Cat. No.
ABIN562456
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7268208
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN1909740
Quantity
200 μL
Datasheet
Datasheet
Latest Publications for our LGMN 抗体
: "Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 23, pp. 9053-8, (2012) (PubMed).: "Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug." in: Molecular pharmaceutics, Vol. 9, Issue 1, pp. 168-75, (2012) (PubMed).
: "Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis." in: Atherosclerosis, Vol. 201, Issue 1, pp. 53-66, (2009) (PubMed).
: "Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase." in: Molecular cell, Vol. 29, Issue 6, pp. 665-78, (2008) (PubMed).
: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, (2005) (PubMed).
Aliases for LGMN 抗体
legumain (LGMN) 抗体legumain (Lgmn) 抗体
legumain L homeolog (lgmn.L) 抗体
legumain (lgmn) 抗体
delta vacuolar processing enzyme (DELTA-VPE) 抗体
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