LEFTY2 产品
(Left-Right Determination Factor 2 (LEFTY2))
Categories
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010].
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Featured LEFTY2 Categories
LEFTY2 抗体
High quality antibodies with extensive validation data.
LEFTY2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
LEFTY2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LEFTY2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7157970
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN7185094
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN6243245
Quantity
400 μL
Datasheet
Datasheet
Recommended LEFTY2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957426
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN843141
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN2535975
Quantity
96 tests
Datasheet
Datasheet
Recommended LEFTY2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309300
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318717
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401626
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LEFTY2 Products
: "Spatially organized in vitro models instruct asymmetric stem cell differentiation." in: Integrative biology : quantitative biosciences from nano to macro, Vol. 3, Issue 12, pp. 1179-87, (2011) (PubMed).: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
: "Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21397-404, (2001) (PubMed).
: "Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 5, pp. 343-57, (2000) (PubMed).
: "Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 20, pp. 11376-81, (1999) (PubMed).
: "lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal." in: Cell, Vol. 94, Issue 3, pp. 287-97, (1998) (PubMed).
Synonyms and alternative names related to LEFTY2
left-right determination factor 2 (LEFTY2), left right determination factor 1 (Lefty1), lefty2 (lft2), left-right determination factor 2 (Lefty2), Left-right determination factor 2 (Lefty2), left-right determination factor 2 (LOC699676), left-right determination factor 2-like (LOC100232580), 6030463A22Rik, AI450052, atv2, AV214969, cb720, EBAF, Ebaf, Ebaf2, fe38b03, LEFTA, Lefta, Leftb, lefty, lefty-1, LEFTYA, Stra3, TGFB4, Tgfb4, wu:fe38b03Protein level used designations for LEFTY2
- TGF-beta-4
- endometrial bleeding-associated factor
- left-right determination factor A
- protein lefty-2
- protein lefty-A
- transforming growth factor beta-4
- left-right determination factor 1
- left-right determination, factor B
- protein lefty-1
- stimulated by retinoic acid gene 3 protein
- endometrial bleeding associated factor
- left-right determination factor B
- left-right determination, factor A
- protein lefty-B
- left-right determination factor 2
- lefty
- left-right determination factor 2-like
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