LEF1 抗体
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
recommended
recommended
LEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
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Popular LEF1 抗体
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Validations
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Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
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WB, ELISA, IHC (p)
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Cat. No.
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Datasheet
Datasheet
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Cat. No.
ABIN6262946
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Datasheet
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
ABIN526531
Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
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Latest Publications for our LEF1 抗体
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991): "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).
: "Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development." in: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).
: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/?-catenin Signaling in Lungs of Neonatal Rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).
: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).
: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).
: "The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of ?-Catenin Following Tail Amputation." in: Journal of molecular neuroscience : MN, (2014) (PubMed).
: "Regulation of ?-catenin nuclear dynamics by GSK-3? involves a LEF-1 positive feedback loop." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 8, pp. 983-99, (2011) (PubMed).
: "LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis." in: Blood, Vol. 116, Issue 16, pp. 2975-83, (2010) (PubMed).
: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, (2010) (PubMed).
Aliases for LEF1 抗体
lymphoid enhancer binding factor 1 (LEF1) 抗体lymphoid enhancer binding factor 1 (lef1) 抗体
lymphoid enhancer-binding factor 1 (lef1) 抗体
lymphoid enhancer binding factor 1 (Lef1) 抗体
lymphoid enhancer factor XLEF-1B (lef1) 抗体
3000002B05 抗体
AI451430 抗体
Lef-1 抗体
LEF-1 抗体
LEF1 抗体
TCF1ALPHA 抗体
TCF7L3 抗体
TCF10 抗体
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