LCK 抗体
(Lymphocyte-Specific Protein tyrosine Kinase (LCK))
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].
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Popular LCK 抗体
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, RNAi
Validations
- (6)
Cat. No.
ABIN561649
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN3023130
Quantity
100 μL
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Datasheet
Reactivity
Human
Application
WB, FACS, IP, ICC
Validations
- (7)
- (4)
Cat. No.
ABIN94422
Quantity
0.1 mg
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Datasheet
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Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, FACS
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- (6)
Cat. No.
ABIN3031644
Quantity
0.4 mL
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Datasheet
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Human
Application
ELISA, IHC, IF, IP
Validations
- (4)
Cat. No.
ABIN7174038
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3043870
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN3031646
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS
Validations
- (3)
Cat. No.
ABIN748553
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (3)
Cat. No.
ABIN517451
Quantity
100 μg
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Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN517452
Quantity
100 μg
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256726
Quantity
100 μL
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6255935
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Pig, Rat
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN987272
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN3020028
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN392101
Quantity
400 μL
Datasheet
Datasheet
Latest Publications for our LCK 抗体
: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria." in: American journal of physiology. Cell physiology, Vol. 298, Issue 3, pp. C740-8, (2010) (PubMed).
: "The effects of membrane compartmentalization of Csk on TCR signaling." in: Biochimica et biophysica acta, (2010) (PubMed).
: "Specific and nonspecific B-cell function in the small intestines of patients with Whipple's disease." in: Infection and immunity, Vol. 78, Issue 11, pp. 4589-92, (2010) (PubMed).
: "Protein tyrosine kinase p56lck-deficiency confers hypersusceptibility to rho-fluorophenylalanine (pFPhe)-induced apoptosis by augmenting mitochondrial apoptotic pathway in human Jurkat T cells." in: Biochemical and biophysical research communications, Vol. 377, Issue 1, pp. 280-5, (2008) (PubMed).
: "Suppression of proximal T cell receptor signaling and lytic function in CD8+ tumor-infiltrating T cells." in: Cancer research, Vol. 67, Issue 23, pp. 11447-54, (2007) (PubMed).
: "Dendritic cells sensitize TCRs through self-MHC-mediated Src family kinase activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 4, pp. 2262-71, (2007) (PubMed).
: "A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation." in: Molecular cancer research : MCR, Vol. 4, Issue 1, pp. 39-45, (2006) (PubMed).
: "HIV/AIDS prevalence and behaviour in drug users and pregnant women in Kashgar Prefecture: case report." in: Harm reduction journal, Vol. 3, pp. 7, (2006) (PubMed).
Aliases for LCK 抗体
LCK proto-oncogene, Src family tyrosine kinase (lck) 抗体LCK proto-oncogene, Src family tyrosine kinase (LCK) 抗体
lymphocyte protein tyrosine kinase (Lck) 抗体
LCK proto-oncogene, Src family tyrosine kinase (Lck) 抗体
Hck-3 抗体
LCK 抗体
Lck1 抗体
Lcktkr 抗体
Lsk 抗体
LSK 抗体
Lskt 抗体
p56
p56Lck 抗体
p56lck 抗体
P56LCK 抗体
pp58lck 抗体
tkl 抗体
YT16 抗体
zgc:136695 抗体
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