LASS5 产品
(LAG1 Homolog, Ceramide Synthase 5 (LASS5))
Categories
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner (By similarity).
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Featured LASS5 Categories
Recommended LASS5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7147471
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN709406
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Horse, Human, Rabbit
Application
WB
Validations
- (1)
Cat. No.
ABIN6742729
Quantity
100 μL
Datasheet
Datasheet
Recommended LASS5 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309179
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3103268
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3129163
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our LASS5 Products
: "Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice." in: American journal of physiology. Endocrinology and metabolism, Vol. 306, Issue 5, pp. E529-42, (2014) (PubMed).: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).
: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).
: "A fluorescent assay for ceramide synthase activity." in: Journal of lipid research, Vol. 53, Issue 8, pp. 1701-7, (2012) (PubMed).
: "D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein ..." in: Biochimie, Vol. 93, Issue 9, pp. 1446-59, (2011) (PubMed).
: "(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1." in: Molecular cancer research : MCR, Vol. 5, Issue 8, pp. 801-12, (2007) (PubMed).
: "Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 33931-8, (2006) (PubMed).
: "LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 33735-8, (2005) (PubMed).
: "Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43452-9, (2003) (PubMed).
Synonyms and alternative names related to LASS5
ceramide synthase 5 (CERS5), ceramide synthase 5 (cers5), ceramide synthase 5 S homeolog (cers5.S), ceramide synthase 5 (Cers5), 2310081H14Rik, AU045339, AW544927, lass5, LASS5, Lass5, trh4, Trh4Protein level used designations for LASS5
- LAG1 homolog, ceramide synthase 5
- LAG1 longevity assurance homolog 5-like
- LAG1 longevity assurance homolog 5
- TRAM homolog 4
- longevity assurance homolog 5
- translocating chain-associating membrane protein homolog 4
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