LARP6 产品
(La Ribonucleoprotein Domain Family, Member 6 (LARP6))
Categories
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9 (By similarity).
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Featured LARP6 Categories
Recommended LARP6 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (8)
- (2)
Cat. No.
ABIN527496
Quantity
50 μg
Datasheet
Datasheet
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Human
Application
ELISA, IHC
Validations
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Cat. No.
ABIN7157812
Quantity
100 μg
Datasheet
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Reactivity
Human
Application
WB, IP
Validations
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Cat. No.
ABIN949443
Quantity
100 μL
Datasheet
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Recommended LARP6 蛋白
Latest Publications for our LARP6 Products
: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." in: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).
: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." in: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).
: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).
: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." in: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).
: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).
: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." in: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).
: "Nonmuscle myosin-dependent synthesis of type I collagen." in: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).
Synonyms and alternative names related to LARP6
La ribonucleoprotein domain family, member 6b (larp6b), La ribonucleoprotein domain family member 6 (LARP6), La ribonucleoprotein domain family, member 6 (Larp6), 5430431G03Rik, ACHN, Achn, AI552438, im:7142825, RGD1308414, wu:fa55b04Protein level used designations for LARP6
- La ribonucleoprotein domain family, member 6
- acheron
- death-associated LA motif protein
- la-related protein 6
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