KLRC3 产品
(Killer Cell Lectin-Like Receptor Subfamily C, Member 3 (KLRC3))
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Recommended KLRC3 抗体
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Reactivity
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Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
- (2)
Cat. No.
ABIN561610
Quantity
100 μg
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Datasheet
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Human
Application
ELISA, IF, IHC
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Cat. No.
ABIN7161649
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN561609
Quantity
50 μL
Datasheet
Datasheet
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Latest Publications for our KLRC3 Products
: "Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 2, pp. 610-6, (2014) (PubMed).: "Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells." in: Cancer letters, Vol. 312, Issue 1, pp. 24-32, (2011) (PubMed).
Synonyms and alternative names related to KLRC3
killer cell lectin-like receptor subfamily C, member 3 (Klrc3), killer cell lectin like receptor C3 (Klrc3), killer cell lectin-like receptor subfamily C, member 3 (KLRC3), killer cell lectin like receptor C3 (KLRC3), Klrc2, KLRC2, NKG2-C, NKG2-E, Nkg2e, NKG2EProtein level used designations for KLRC3
- killer cell lectin-like receptor subfamily C, member 2
- natural killer cell group 2E cell receptor
- killer cell lectin-like receptor subfamily C, member 3
- NKG2-C2
- NKG2-E type II integral membrane protein
- NK cell receptor E
- NKG2-E-activating NK receptor
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