KLRC2 产品
(Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Featured KLRC2 Categories
Recommended KLRC2 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (5)
Cat. No.
ABIN652570
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7440197
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN739950
Quantity
100 μL
Datasheet
Datasheet
Recommended KLRC2 ELISA试剂盒
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Reactivity
Analytical Method
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Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN417112
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96 tests
Datasheet
Datasheet
Recommended KLRC2 蛋白
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Reactivity
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Cat. No.
ABIN7275345
Quantity
100 μg
Datasheet
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Reactivity
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Source
HEK-293 Cells
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Cat. No.
ABIN7275336
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Source
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Validations
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Cat. No.
ABIN7275341
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KLRC2 Products
: "NKG2C(+)CD57(+) Natural Killer Cell Expansion Parallels Cytomegalovirus-Specific CD8(+) T Cell Evolution towards Senescence." in: Journal of immunology research, Vol. 2016, pp. 7470124, (2016) (PubMed).: "KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells." in: European journal of immunology, Vol. 46, Issue 1, pp. 185-91, (2016) (PubMed).
: "CD2-CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection." in: European journal of immunology, Vol. 46, Issue 10, pp. 2420-2425, (2016) (PubMed).
: "Influenza Vaccination Generates Cytokine-Induced Memory-like NK Cells: Impact of Human Cytomegalovirus Infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 1, pp. 313-25, (2016) (PubMed).
: "Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo." in: PLoS pathogens, Vol. 12, Issue 8, pp. e1005788, (2016) (PubMed).
: "New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells." in: Journal of leukocyte biology, Vol. 100, Issue 3, pp. 471-9, (2016) (PubMed).
: "Association of high HLA-E expression during acute cellular rejection and numbers of HLA class I leader peptide mismatches with reduced renal allograft survival." in: Immunobiology, Vol. 222, Issue 3, pp. 536-543, (2016) (PubMed).
: "Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 9, pp. 4524-36, (2015) (PubMed).
: "Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 10, pp. 4657-67, (2015) (PubMed).
: "Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 7, pp. 3513-25, (2015) (PubMed).
Synonyms and alternative names related to KLRC2
killer cell lectin like receptor C2 (KLRC2), killer cell lectin-like receptor subfamily C, member 2 (KLRC2), CD159c, NKG2-C, NKG2CProtein level used designations for KLRC2
- CD159 antigen-like family member C
- NK cell receptor C
- NKG2-C type II integral membrane protein
- NKG2-C-activating NK receptor
- NKG2-FE
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