KLRC1 抗体
(Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
recommended
KLRC1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB21885 unconjugated
recommended
recommended
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Find KLRC1 抗体 for a variety of species such as anti-Human KLRC1, anti-Mouse KLRC1, anti-Guinea Pig KLRC1. The species listed below are among those available. Click on a link to go to the corresponding products.
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Latest Publications for our KLRC1 抗体
: "Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells." in: Scientific reports, Vol. 9, Issue 1, pp. 14916, (2019) (PubMed).: "The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells." in: Biochemical and biophysical research communications, Vol. 478, Issue 1, pp. 213-20, (2016) (PubMed).
: "Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo." in: PLoS pathogens, Vol. 12, Issue 8, pp. e1005788, (2016) (PubMed).
: "IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 1, pp. 85-96, (2016) (PubMed).
: "CD3(bright)CD56(+) T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients." in: Scientific reports, Vol. 6, pp. 25567, (2016) (PubMed).
: "Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125544, (2015) (PubMed).
: "Overexpression of CD85j in TNBC patients inhibits Cetuximab-mediated NK-cell ADCC but can be restored with CD85j functional blockade." in: European journal of immunology, Vol. 45, Issue 5, pp. 1560-9, (2015) (PubMed).
: "WNT5A transforms intestinal CD8αα⁺ IELs into an unconventional phenotype with pro-inflammatory features." in: BMC gastroenterology, Vol. 15, pp. 173, (2015) (PubMed).
: "Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 5, pp. 2141-8, (2015) (PubMed).
: "Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 98, (2015) (PubMed).
Aliases for KLRC1 抗体
killer cell lectin like receptor C1 (Klrc1) 抗体killer cell lectin like receptor C1 (KLRC1) 抗体
NKG2-A/NKG2-B type II integral membrane protein-like (NKG2A) 抗体
killer cell lectin-like receptor subfamily C, member 3 (KLRC3) 抗体
killer cell lectin-like receptor subfamily C, member 1 (KLRC1) 抗体
killer cell lectin-like receptor subfamily C, member 1 (Klrc1) 抗体
CD159A 抗体
CD159a 抗体
KLRC1 抗体
NKG2 抗体
NKG2-A 抗体
NKG2A 抗体
NKG2B 抗体
rNKG2A 抗体
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