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KLHL3 产品

(Kelch-Like 3 (KLHL3))

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This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)\; a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].

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Featured KLHL3 Categories

KLHL3 抗体

High quality antibodies with extensive validation data.

KLHL3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KLHL3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7184471
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6262847
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7157290
Quantity 100 μg
Datasheet Datasheet

Recommended KLHL3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229034
Quantity 96 tests
Datasheet Datasheet

Recommended KLHL3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308817
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1793163
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3082516
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KLHL3 Products

Shibata, Zhang, Puthumana, Stone, Lifton: "Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 19, pp. 7838-43, (2013) (PubMed).

Synonyms and alternative names related to KLHL3

kelch like family member 3 (KLHL3), kelch-like 3 (Klhl3), kelch-like family member 3 (Klhl3), 7530408C15Rik, AI430941, EG627648, PHA2D, RGD1565218

Protein level used designations for KLHL3

  • kelch-like protein 3
  • kelch-like 3
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