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KLF8 产品

(Kruppel-Like Factor 8 (KLF8))

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This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

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Featured KLF8 Categories

KLF8 抗体

High quality antibodies with extensive validation data.

KLF8 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KLF8 抗体

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Datasheet
Reactivity Human
Application WB, IP
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Cat. No. ABIN524709
Quantity 100 μL
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Reactivity Human
Application WB, ELISA
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Cat. No. ABIN524711
Quantity 100 μg
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Reactivity Human
Application WB, IF
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Cat. No. ABIN524708
Quantity 50 μg
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Recommended KLF8 蛋白

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Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1308766
Quantity 10 μg
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3082794
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Latest Publications for our KLF8 Products

Zheng, Zheng, Meng, Yan, He, Liu: "LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis." in: Cancer cell international, Vol. 19, pp. 302, (2019) (PubMed).

Yan, Zhang, Wu, Wu, Zhang, Shi, Zhao, Nan, Chen, Wang, Cheng, Li, Bai, Liu, Wang: "KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2." in: Oncotarget, Vol. 6, Issue 28, pp. 25402-17, (2015) (PubMed).

Han, Han, Sun, Zan, Zhou, Xu, Yao, Liu: "Krüppel?like factor expression and correlation with FAK, MMP?9 and E?cadherin expression in hepatocellular carcinoma." in: Molecular medicine reports, Vol. 8, Issue 1, pp. 81-8, (2013) (PubMed).

Schnell, Romagna, Jaehnert, Albrecht, Eigenbrod, Juerchott, Kretzschmar, Tonn, Schichor: "Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation." in: PLoS ONE, Vol. 7, Issue 1, pp. e30429, (2012) (PubMed).

Fu, Li, Wu, Yang, Mo, Huang, Xia, Ding, Liu, Zhu: "Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1255-65, (2010) (PubMed).

Li, Yang, Sun, Xu, Zhou, Qiu, Ke, Cui, Wang, Wang, Liu, Fan: "Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma." in: Gastroenterology, Vol. 139, Issue 6, pp. 2146-2157.e12, (2010) (PubMed).

Ding, Grammer, Nelson, Guan, Stewart, Gladson: "p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6802-15, (2005) (PubMed).

van Vliet, Turner, Crossley: "Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription." in: Nucleic acids research, Vol. 28, Issue 9, pp. 1955-62, (2000) (PubMed).

Synonyms and alternative names related to KLF8

Kruppel like factor 8 (KLF8), Kruppel-like factor 8 (klf8), Kruppel-like factor 8 (Klf8), Kruppel-like factor 8 (KLF8), A830097P10Rik, BKLF3, klf8, Klf8-ps1, RGD1565831, ZNF74, ZNF741

Protein level used designations for KLF8

  • Krueppel-like factor 8
  • kruppel-like factor 8
  • Kruppel-like factor 8
  • basic krueppel-like factor 3
  • basic kruppel-like factor 3
  • zinc finger protein 741
  • Kruppel-like factor 8, pseudogene 1
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