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Annexin V ELISA 试剂盒

ANXA5 适用: 化学剂 Colorimetric Sandwich ELISA
产品编号 ABIN930753
发货至: 中国
  • 抗原 See all Annexin V (ANXA5) ELISA试剂盒
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    适用
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    化学剂
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    Analytical Method
    Quantitative
    产品特性
    ELISA kit for the detection of Annexin V in the research laboratory
    Alternative Names: Annexin V ELISA kit
    Top Product
    Discover our top product ANXA5 ELISA Kit
  • 应用备注
    Optimal conditions to be determined by end-user
    板类型
    Pre-coated
    实验流程

    The Antiannexin V IgG/IgM is an indirect solid phase enzyme immunometric assay (ELISA). It is designed for the quantitative measurement of IgG or IgM class autoantibodies directed against annexin V. The microplate is coated with highly purified human recombinant annexin V. The microplate can be divided into 12 modules of 8 wells each or can be used completely for 96 determinations. Each well can be separated from the module (

    限制
    仅限研究用
  • 储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原 See all Annexin V (ANXA5) ELISA试剂盒
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    别名
    Annexin V (ANXA5 产品)
    物质类
    Chemical
    背景
    Annexin V, also known as placental anticoagulant protein I (PAP I), not only belongs to a family of proteins that bind to phospholipids in a calcium dependent manner, but is also a potent vascular anticoagulant protein. Annexin V is necessary to maintain placental integrity and may have a thrombo-regulatory effect at the materno-fetal interface, as shown in a murine model. It has been suggested, that interference of anti-annexin V antibodies with the annexin V shield on the placental villi leads to the exposure of anionic procoagulant phospholipids. Anionic procoagulant phospholipids are known to enhance blood coagulation processes in the placental vasculature, and may be an important contributory factor of thrombosis and recurrent loss of pregnancy in the APS. Anti-annexin V antibodies are not only highly specific for APS, but also elevated levels of antibodies are detected in patients with systemic lupus diseases (SLE). It has been suggested that anti-annexin V autoantibodies may influence in the clinical course of rheumatoid arthritis. A significantly high frequency of arterial or venous thrombosis is found in patients with anti-annexin V antibodies. And are a significant risk factor for recurrent miscarriages in SLE patients.
    Synonyms: Annexin V ELISA kit.
    途径
    Apoptosis
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